Comparing Secretome and Platelet-Rich Plasma Injections for Hair Growth in Adults with Androgenetic Alopecia at Prof. Dr. I.G.N.G. Ngoerah Hospital

What this Trial Is About

Researchers are comparing two injection treatments, secretome and intradermal platelet-rich plasma PRP, to see how they affect hair density and the ratio of terminal to vellus hairs in people with androgenetic alopecia. This randomized controlled clinical study takes place at Prof. Dr. I.G.N.G. Ngoerah General Hospital and focuses on adults aged 25 to 59 years with specific stages of hair loss. The purpose is to evaluate which treatment better supports hair growth and density. Participants receive either umbilical cord mesenchymal stem cell-derived secretome or platelet-rich plasma injections. Both treatments involve intradermal injections spaced 1 cm apart at the alopecia site and are administered every 2 weeks for a total of 8 weeks. The secretome and PRP injections are given under controlled conditions, with patients randomly assigned to one of the two groups. During the study, hair density and the terminal-to-vellus hair ratio are measured before treatment, at 8 weeks after intervention, and again during follow-up visits at months 3, 6, and 9. Evaluations use trichoscopy or dermoscopy to monitor changes. Participants provide informed consent and are monitored throughout the study to track treatment effects and safety. The total study duration includes treatment and follow-up periods to assess long-term outcomes.

Secretome vs. PRP Injections for Hair Density and Growth in Androgenetic Alopecia Patients