Actively Recruiting
Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients
Led by Beijing Shijitan Hospital, Capital Medical University · Updated on 2026-01-07
306
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A multi-center, prospective, randomized, double-blind, no-inferiority clinical trial designed to assess the the safety and efficacy of remazolam besylate in sedation of critically ill mechanically ventilated patients after surgery compared to dexmedetomidine.
CONDITIONS
Official Title
Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 64 years old
- Undergoing non-cardiac elective surgery
- Received general anesthesia
- May have combined regional tissue anesthesia
- Admitted to ICU with tracheal intubation after general anesthesia
- Expected mechanical ventilation time more than 24 hours
- Requires light or moderate sedation
You will not qualify if you...
- History of intracranial surgery or severe neurological or spinal cord disease
- Diagnosis of schizophrenia, epilepsy, or Parkinson's disease
- Coma, severe dementia, or language barrier before surgery
- Cardiac dysfunction or arrhythmia
- Severe liver dysfunction (Child-Pugh C class)
- Severe kidney dysfunction
- Use of dexmedetomidine or remifentanil besylate within 24 hours before or during surgery
- Pregnancy or lactation
- Use of any investigational drug within 30 days before surgery
- Refusal to participate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Shijitan Hospital.CMU
Beijing, Beijing Municipality, China, 100038
Actively Recruiting
Research Team
Y
Yuefu Wang, doctor
CONTACT
D
Dandan Liu, master
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here