Actively Recruiting
Selective CT for Anticoagulated Head Injured Patients
Led by Dr. Kerstin de Wit · Updated on 2026-04-14
4000
Participants Needed
7
Research Sites
295 weeks
Total Duration
On this page
Sponsors
D
Dr. Kerstin de Wit
Lead Sponsor
C
Canadian Institutes of Health Research (CIHR)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1. Derive and externally validate a new highly sensitive and maximally specific clinical decision rule for the exclusion of traumatic brain injury in head-injured ED patients who take anticoagulant medications; and, 2. Estimate the sensitivity and specificity of existing head injury clinical decision rules in head-injured ED patients who take anticoagulant medications.
CONDITIONS
Official Title
Selective CT for Anticoagulated Head Injured Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 16 years
- Presents to the emergency department after a head injury
- Patient has a head CT in the emergency department
- Is a current anticoagulant user
You will not qualify if you...
- Head injury occurred more than 48 hours before arrival to the emergency department
- Penetrating head injury
- Previously enrolled in the study
- Patient lives outside the hospital's catchment area
- Transferred from another emergency department after neuroimaging
- Not managed by emergency or trauma physician in the emergency department
- Leaves the emergency department before completing medical assessment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
University of British Columbia
Vancouver, British Columbia, Canada, V6T 1Z4
Not Yet Recruiting
2
Hamilton Health Sciences Corporation
Hamilton, Ontario, Canada, L8L 2X2
Not Yet Recruiting
3
Kingston Health Sciences Centre
Kingston, Ontario, Canada, N3T 6P9
Actively Recruiting
4
Ottawa Hospital Research Institute
Ottawa, Ontario, Canada, K1H 8L6
Not Yet Recruiting
5
Sinai Health
Toronto, Ontario, Canada, M5G 1X5
Not Yet Recruiting
6
Hôpital du Sacré-Cœur de Montréal
Montreal, Quebec, Canada, H4J 1C5
Not Yet Recruiting
7
CHU de Québec - Université Laval
Québec, Quebec, Canada, G1R 2J6
Not Yet Recruiting
Research Team
N
Natasha Clayton, CRA, RA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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