Actively Recruiting
Self-administered COgnitive Personalized Training in Early Psychosis
Led by Centre Hospitalier St Anne · Updated on 2024-10-10
240
Participants Needed
1
Research Sites
322 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The overall objective of SCOPe is to improve early intervention in psychosis by providing an innovative eHealth tool that will enable personalized cognitive training, adapted to the individual's cognitive abilities. Cognitive remediation improves quality of life and functional outcome in patients with chronic psychosis. It would even be more efficacious in the early phase of psychosis by tackling the negative impact of psychosis on education achievement and employment. However, cognitive dysfunctions are often overlooked in FEP and cognitive remediation is not always accessible. New technologies can provide us with youth-friendly, non-stigmatizing tools, such as self administered, training applications so that all first-line clinical settings or professionals, and in fine all patients, can have access, wherever they live, to personalized cognitive training focusing on impaired functions. Early psychosis can be associated with inflammation, metabolic deficiency, as well as early structural brain anomalies that reflect brain plasticity abilities and could influence the prognosis and response to cognitive training. Our background hypothesis is that promoting neuroplasticity by cognitive training could attenuate or reverse early cognitive deficits and improve the overall functional outcome in young patients experiencing FEP and that this effect is modulated by individual brain plasticity abilities.
CONDITIONS
Official Title
Self-administered COgnitive Personalized Training in Early Psychosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 16 to 35 years
- Both genders
- Seeking help at one of the recruiting centers
- Newly diagnosed with a first episode of psychosis according to CAARMS criteria within the past year
- Written informed consent signed (and from a legal guardian if underage)
You will not qualify if you...
- Severe and unstabilized medical conditions
- Insufficient reading or French language skills
- No medical insurance
- Participation in another intervention trial
- Enforced hospitalization (ASPDT, ASPPI, ASPRE)
- Intellectual disability (IQ < 70) or sensorimotor deficits incompatible with cognitive training
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Groupe Hospitalier Universitaire Paris - Psychiatrie et Neurosciences, (GHU Paris)
Paris, France
Actively Recruiting
Research Team
M
Marie Odile KREBS, PROFESSEUR
CONTACT
L
Linda SCORIELS, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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