Actively Recruiting
Self-Administered Gaming and Exercise at Home (SAGEH)
Led by Johns Hopkins University · Updated on 2025-07-18
60
Participants Needed
1
Research Sites
217 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
S
Sheikh Khalifa Stroke Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims at comparing manual function outcomes between the standard of care and additional self-administered hand therapy after stroke. Strokes are common neurological injuries, and although rates of survival have increased in recent decades, survivors often continue to experience deficiencies in hand dexterity and bimanual function. Most motor recovery takes place within the first 3 months after a stroke. This initial period is necessary for stabilizing the patient but also provides different opportunities to foster motor recovery. Functional gains, including instances after the post-acute period, have been observed after regular and frequent (high dosage) therapy, suggesting that recovery is likely influenced by practice-driven sensorimotor learning. These findings motivate the implementation of daily therapeutic regimes beyond post-stroke hospitalization and basic motor function, aiming instead at addressing overlooked deficiencies in manipulation and bimanual coordination. While some hand therapy is often provided during outpatient therapy visits (the standard of care), self-administered sessions play a large role in implementing additional daily therapy. As a result, the investigators are interested in both the implementation of self-administered regimes and measuring clinical outcomes with and without self-administered therapy.
CONDITIONS
Official Title
Self-Administered Gaming and Exercise at Home (SAGEH)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 21 years and over
- Stroke confirmed by CT or MRI within the previous 6 weeks
- Arm and/or hand impairment caused by the stroke
- Meet JSTTEP criteria and are enrolled in JSTTEP
- Admitted to Johns Hopkins Hospital inpatient stroke service
- Proficient in speaking and reading English
- Willing and able to be contacted remotely for telemedicine
- No history of prior ischemic or hemorrhagic stroke with motor deficits (prior stroke without upper limb motor symptoms allowed)
- Ability to give informed consent
You will not qualify if you...
- Arm impairment too severe (Fugl-Meyer Upper Extremity score under 40) at baseline testing
- Recent Botox injection to upper limb since stroke onset
- Physical or neurological conditions interfering with study or motor function tests (e.g., severe arthritis, neuropathy, Parkinson's disease)
- Terminal illness with life expectancy less than 6 months
- Unable to sit in a chair and perform hand exercises for 20 minutes at a time
- Cognitive impairment with Montreal Cognitive Assessment score 20 or below
- Social or personal circumstances preventing telemedicine follow-up
AI-Screening
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Trial Site Locations
Total: 1 location
1
Johns Hopkin
Baltimore, Maryland, United States, 21287-6953
Actively Recruiting
Research Team
S
Steven R. Zeiler, M.D., Ph.D.
CONTACT
A
Arnold Gomez, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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