Actively Recruiting
Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors
Led by Tata Memorial Centre · Updated on 2026-02-24
600
Participants Needed
1
Research Sites
89 weeks
Total Duration
On this page
Sponsors
T
Tata Memorial Centre
Lead Sponsor
B
Bhabha Atomic Research Centre
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to evaluate the feasibility and accuracy of a self-administered remote neurological examination using the "Iskhaa" mobile application in patients with brain tumors aged above 5 years who are able to follow app-based instructions. The main questions it aims to answer are: 1. Development of a mobile application equipped with symptom assessment and recording videos as patients perform specific neurological tasks. 2. Development and validation of the AI model to detect functional changes and predict subsequent neurological deterioration. Participants will: 1. Use the Iskhaa mobile application to perform guided self-neurological examinations following pre-recorded video instructions. 2. Complete EORTC QLQ-C30 and BN20 questionnaires for quality of life assessment. 3. Record and upload videos (e.g., speech, walking, limb movements) using their mobile camera for analysis. 4. In Phase 1 (onsite), 100 participants will use the app under supervision to ensure usability and accuracy. 5. In Phase 2 (offsite), 500 participants will use the app independently at home for monthly self-assessments, with reminders and follow-up support. 6. Continue routine clinic visits every 3-6 months and imaging every 6-12 months as per standard clinical care. The study will compare app-recorded data with physician assessments to determine agreement and validity of remote neurological monitoring using artificial intelligence analysis.
CONDITIONS
Official Title
Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of brain tumors confirmed by histopathology or radiology
- Age over 5 years
- Patient or caregiver has access to an Android smartphone and can install the mobile app
- Expected survival longer than 6 months during study participation
- Signed patient consent or parent consent/child assent as appropriate
You will not qualify if you...
- Patient or caregiver unable to follow instructions or use the mobile app reliably
- Severe cognitive or psychiatric problems interfering with app use or following instructions
- Karnofsky or Lansky Performance Status less than 50
- Terminal illness with life expectancy less than 6 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Tata Memorial Centre
Mumbai, Maharashtra, India, 400012
Actively Recruiting
Research Team
D
Dr Archya Dasgupta, Radiation Oncology, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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