User inclusion criteria:

• Any gender, age 18 years or older
• Motor complete or incomplete SCI at any level
• ≥ 6 months post SCI
• Able and willing to attend 9 visits to the center, including sessions of training and assessments of one-to-three hours duration
• Able to read, understand, and provide informed consent.
• Patients affiliated to a social security system.

User exclusion criteria:

• Diagnosis of neurological injury other than SCI;
• Progressive condition that would be expected to result in changing neurological status;
• Severe concurrent medical disease, illness or condition judged to be contraindicated by the site physician;
• Unhealed or unstable traumatic or high impact lower extremity fracture of any duration that is, in the clinical judgement of the study physician, exclusionary for standing and walking;
• Individual with history of osteoporotic fracture and / or pathology or treatment causing secondary osteoporosis.
• Untreatable severe spasticity judged to be contraindicated by the site physician;
• Untreated/uncontrolled hypertension, as judged to be contraindicated by the site physician;
• Unresolved orthostatic hypotension (change from baseline seated BP to a fall in 20mmHg SBP and/or fall in 10mmHG DBP and symptoms when standing), or as judged to be contraindicated by the site physician;
• Open or unhealed skin pressure sores, abrasions, or bruises at any of the contact points of the exoskeleton;
• Morphological contraindications to the use of the device;
• Uncorrectable leg length discrepancy over 2 cm (about 0.79 in) when using additional correction tools;
• Unable to effectively operate the device with a controller, due to functional and/or cognitive impairment, evaluated based on the ability to manipulate the joystick in all direction, press and identify buttons on the controller.
• Improper fitting in the device;
• Psychopathology documentation in the medical record that may conflict with study objectives;
• Pregnancy or women who plan to become pregnant during the study period;
• Concurrent participation in another interventional trial;
• Uncontrolled autonomic dysreflexia;
• Ventilator use at the time of the exoskeleton use.
• Patient under legal protection.

Companion inclusion criteria

• Any gender, age 18 years or older.
• Willingness to attend 9 to 10 visits to the center, including sessions of training and assessments of one-to-three hours duration with the SCI user.
• Able to read, understand and provide informed consent.

Companion exclusion criteria:

• Inability to communicate due to cognitive and language disorders;
• Any disease, concomitant injury, or condition that interferes with the performance or interpretation of the protocol- specified assessments;
• Insufficient strength and performance capability, evidenced by the ability to hold and retain the device in case of unbalance/fall;
• Insufficient availability to complete the study;
• Concurrent participation in another interventional trial.

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety