Actively Recruiting
Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]
Led by Abramson Cancer Center at Penn Medicine · Updated on 2025-08-14
204
Participants Needed
2
Research Sites
126 weeks
Total Duration
On this page
Sponsors
A
Abramson Cancer Center at Penn Medicine
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to evaluate the effectiveness of a standardized lymphedema and fibrosis self-management program (LEF-SMP) to improve LEF self-management and reduce LEF-associated symptom burden, functional deficits, and improve quality of life in head and neck cancer (HNC) survivors.
CONDITIONS
Official Title
Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 18 years of age
- Completed primary treatment for head and neck cancer
- No evidence of cancer currently
- Completed initial therapy for head and neck lymphedema
- Unable to obtain further lymphedema therapy due to barriers
- History of lymphedema on the face and neck, with or without fibrosis
- Able to understand English to complete questionnaires
- Able to perform self-care activities for LEF management
- Able to provide informed consent
- Have an electronic device (computer, tablet, iPad, or smartphone) and internet access at home
- Have a valid email address
You will not qualify if you...
- Recurrent or metastatic cancer
- Any other active cancer
- Acute infection
- Acute congestive heart failure
- Acute renal failure
- Cardiac or pulmonary edema
- Sensitive carotid sinus
- Severe carotid blockage
- Uncontrolled hypertension
- Venous thrombosis
- Pregnant people
- Incarcerated patients
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
2
Barbara Murphy
Nashville, Tennessee, United States, 37232
Actively Recruiting
Research Team
J
Jie Deng, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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