Actively Recruiting
Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases
Led by King's College London · Updated on 2025-12-22
20
Participants Needed
2
Research Sites
57 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the study is to generate patient-derived organoids (PDOs) from brain resection or biopsied extra-cranial metastases. The preliminary data collected will be used to assess the ability of PDOs to predict patients' treatment response and their radio-sensitivity and chemo-sensitivity can be correlated with their survival outcome.
CONDITIONS
Official Title
Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Breast cancer patients with brain metastases who are suitable for surgical resection or breast cancer patients with extra-cranial metastases undergoing surgical resection or biopsy
- Age > 18 years old
You will not qualify if you...
- Patients unable to give informed consent, such as those with mental disabilities or who are considered vulnerable adults
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Guy's and St. Thomas NHS Foundation Trust
London, United Kingdom, SE1 9RT
Actively Recruiting
2
King's College Hospital NHS Foundation Trust
London, United Kingdom, SE5 9RS
Actively Recruiting
Research Team
A
Anthony Kong
CONTACT
C
Christiana Cattaneo
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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