Sources of Added Sugars in Young Children, Adolescents, and Adults with Low and High Intakes of Added Sugars.
Regan L Bailey, Victor L Fulgoni, Alexandra E Cowan...
https://pubmed.ncbi.nlm.nih.gov/29342109/Actively Recruiting
Led by Nana Gletsu Miller · Updated on 2026-08-06
63
Participants Needed
3
Research Sites
N/A
Total Duration
Researchers are evaluating whether replacing sugary sodas with unsweetened, flavored sparkling waters, progressively sugar-reduced sodas, or plain water can reduce added sugar intake and improve health in BlackAfrican American and Latine adolescents with obesity who prefer sweet-tasting beverages. The study focuses on adolescents aged 12 to 18 who have a strong liking for sweet beverages and consume sugary sodas regularly. The trial aims to understand if changing beverage preferences leads to better diet quality and cardiometabolic health. Participants will be randomly assigned to one of three groups replacing sugary sodas with flavored unsweetened sparkling water, replacing sodas with beverages that gradually reduce sugar content over four weeks ending with unsweetened sparkling water, or replacing sodas with plain still water as a control. The intervention lasts for four weeks, during which participants will replace all sugary sodas with their assigned study beverages. During the 8-week study period, participants will complete taste tests at baseline, week 2, week 4, and week 8 to assess their liking and perception of sweetness. Dietary recalls, body measurements including height, weight, and waist circumference, blood pressure readings, and blood samples measuring fasting glucose, insulin, and triglycerides will be collected at baseline, week 4, and week 8. Researchers will monitor compliance with beverage consumption and evaluate changes in sugar liking, diet quality, and cardiometabolic markers, including serum triglycerides and insulin resistance.
CONDITIONS
A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents
N
Nana Gletsu Miller, PhD
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Nana Gletsu Miller
Lead Sponsor
Purdue University
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Flavored, Unsweetened Sparkling Water | Progressively Reduced Sugar Beverages | Plain Still Water |
|---|---|---|---|
| What it is | Adolescents replaced all sugar-sweetened sodas with flavored, unsweetened sparkling waters for 4 weeks. | Adolescents consumed beverages with gradually decreasing sugar concentrations each week, ending with unsweetened sparkling water. | Adolescents replaced all sugar-sweetened sodas with plain still water for 4 weeks. |
| Role in the trial | Experimental arm testing full sugar elimination using flavored unsweetened sparkling water. | Experimental arm assessing gradual sugar reduction in beverage exposure. | Active comparator arm evaluating replacement with plain water instead of sweetened alternatives. |
| Primary use | Aims to study whether replacing sugary sodas with flavored unsweetened sparkling water alters participants’ liking for sweetness and metabolic outcomes. | Aims to study whether gradual reduction of sugar in beverages can shift taste preference and metabolic markers over time. | Serves as a comparator for sensory and metabolic effects of full sugar removal with still water. |
| How it is given or performed | Participants exclusively drink flavored unsweetened sparkling water instead of sugary sodas for 4 weeks. | Participants drink beverages with reduced sugar every week, ending with unsweetened sparkling water. | Participants exclusively drink plain still water instead of sugary sodas for 4 weeks. |
| Important limitations | Adherence to beverage replacement protocols can be challenging outside structured settings. The short intervention period may limit the detection of long-term metabolic changes. | Gradual reduction models may not fully mimic real-world beverage choices or preferences. Metabolic effects may depend on baseline sugar intake and participant engagement. | Switching to plain water may be less acceptable for adolescents used to sweet flavors, possibly affecting compliance. Sensory factors and cultural preferences are important considerations. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 4 weeks
Participants replace sugary sodas with assigned study beverages: unsweetened sparkling water, progressively reduced sugar sodas, or plain water for 4 weeks.
Visits at baseline, week 2, and week 4 for assessments
Duration - 4 weeks
Participants continue monitoring without beverage replacement for 4 weeks to assess lasting changes.
Visit at week 8 for final assessments
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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https://pubmed.ncbi.nlm.nih.gov/39037472/Nana Gletsu Miller
Lead Sponsor
Purdue University
Collaborating Sponsor