Actively Recruiting

Phase Not Applicable
Age: 12Years - 18Years
All Genders
Healthy Volunteers
ID07223151

Trading Sugar for Sparkles in Adolescents: A Sensory Approach for Reducing Added Sugar From Sweetened Beverages

Led by Nana Gletsu Miller · Updated on 2025-10-31

63

Participants Needed

3

Research Sites

N/A

Total Duration

On this page

Sponsors

N

Nana Gletsu Miller

Lead Sponsor

P

Purdue University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to evaluate whether replacing sugary sodas with unsweetened, flavored sparkling waters can reduce added sugar intake and improve health among Black/African American and Latine adolescents with obesity who prefer sweet-tasting beverages. The study focuses on adolescents aged 12 to 18 who are "sweet-likers," meaning they prefer higher sugar concentrations in drinks. The main questions explore if changing beverage choices affects liking for sugary drinks and water, and whether this leads to better diet quality and cardiometabolic health. Participants will be randomly assigned to one of three groups for a 4-week intervention: replacing sodas with flavored unsweetened sparkling water, replacing sodas with beverages that gradually reduce sugar concentration weekly until unsweetened sparkling water, or replacing sodas with plain still water as a control. Following the intervention, there is a 4-week follow-up period to track changes. All sugary sodas will be replaced with assigned study beverages during the intervention. Throughout the 8 weeks, participants will complete taste tests to measure their liking and perception of sweetness at baseline, week 2, week 4, and week 8. Researchers will collect dietary recalls, body measurements like height, weight, and waist circumference, blood pressure, and blood samples to measure glucose, insulin, and triglycerides at baseline, week 4, and week 8. The study aims to see if changes in sweetness preference relate to improvements in health markers and diet quality while monitoring participant compliance and any side effects.

CONDITIONS

Brief Title

A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents

Who Can Participate

Age: 12Years - 18Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adolescents aged 12 to 18 who prefer higher sugar concentrations in beverages (0.3M or 10.3% sucrose or above).
  • Have obesity with a body mass index (BMI) above the 95th percentile.
  • Willing to drink the assigned study beverages.
  • Not currently dieting or changing diet.
Not Eligible

You will not qualify if you...

  • Pregnancy, as it affects taste perception.
  • Allergy or intolerance to any study beverages.
  • Diagnosis of type 1 or type 2 diabetes.
  • Regular consumption of unsweetened sparkling water two or more times per week.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 4 weeks

Participants replace their usual sugary sodas with assigned study beverages for 4 weeks. Depending on their group, they will consume either flavored unsweetened sparkling water, progressively reduced sugar beverages, or plain still water.

Baseline visit and visits at Week 2 and Week 4

Follow-up

Duration - 4 weeks

Participants continue to be monitored for changes in beverage liking, diet quality, and cardiometabolic markers during a 4-week post-intervention period.

1 visit at Week 8

Trial Site Locations

Total: 3 locations

1

Indiana University School of Public Health - Bloomington

Bloomington, Indiana, United States, 47405

Not Yet Recruiting

2

Indiana University Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

3

Purdue University

West Lafayette, Indiana, United States, 47907

Actively Recruiting

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Research Team

N

Nana Gletsu Miller, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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Frequently Asked Questions

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Published Research Related To This Trial

Consumption of added sugars from liquid but not solid sources predicts impaired glucose homeostasis and insulin resistance among youth at risk of obesity.

Jiawei Wang, Kelly Light, Mélanie Henderson...

https://pubmed.ncbi.nlm.nih.gov/24198307

Sources of Added Sugars in Young Children, Adolescents, and Adults with Low and High Intakes of Added Sugars.

Regan L Bailey, Victor L Fulgoni, Alexandra E Cowan...

https://pubmed.ncbi.nlm.nih.gov/29342109

Poor Adherence to US Dietary Guidelines for Children and Adolescents in the National Health and Nutrition Examination Survey Population.

Emilyn C Banfield, Yan Liu, Jennifer S Davis...

https://pubmed.ncbi.nlm.nih.gov/26391469

Secondary Analysis of Sweetness Liking from Pilot Study Replacing Sugar Sweetened Soda with Flavored, Unsweetened Sparkling Water.

Vinícius Valicente, Nana Gletsu-Miller, Cordelia A Running

https://pubmed.ncbi.nlm.nih.gov/39037472