Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05108090

Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

Led by Indiana University · Updated on 2025-06-11

94

Participants Needed

1

Research Sites

253 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to research if a type of biopsy known as sentinel lymph node biopsy (SLNB) can help in determining the rate of tumor deposits that are hard to detect and identify in node-negative cutaneous squamous cell carcinoma of the head or neck.

CONDITIONS

Official Title

Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients ≥ 18 years old at the time of informed consent
  • Ability to provide written informed consent and HIPAA authorization
  • Primary or recurrent invasive cutaneous squamous cell carcinoma of the head or neck, clinically staged T2-T4 based on AJCC staging
  • Clinically and radiographically regional node-negative (no evidence of regional lymph node metastasis or distant metastasis)
  • Able to undergo general anesthesia for sentinel lymph node biopsy
  • Able to undergo CT scan with contrast or MRI with contrast
  • Undergo surgical resection (Moh's or micrographic resection or standard excision with sentinel lymph node biopsy) within 8 weeks of imaging
Not Eligible

You will not qualify if you...

  • Clinical evidence of satellite lesions, in-transit, regional nodal or distant metastases
  • Known biopsy proven synchronous primary cutaneous squamous cell carcinoma
  • Pregnant patients
  • Patients unable to undergo general anesthesia
  • Patient unable to receive contrasted imaging studies
  • Patient unable to receive and/or allergic to 99m-Technetium sulfur colloid

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Indiana University Melvin & Bren Simon Cancer Center

Indianapolis, Indiana, United States, 46202

Actively Recruiting

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Research Team

A

Azeezat Yekinni

CONTACT

J

Jessica Yesensky, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

1

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