Actively Recruiting

Age: 18Years +
All Genders
NCT07022041

Sepsis and Hospital Mortality

Led by University of Calabria · Updated on 2025-08-07

100

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Sepsis is one of the leading causes of hospital mortality, with a rate of approximately 20% (World Health Organization) among vulnerable patients admitted to high-intensity care units such as CCUs and inpatient wards. Currently, diagnostic criteria such as the Systemic Inflammatory Response Syndrome (SIRS) and the Sequential Organ Failure Assessment (SOFA) score, although widely used, lack sufficient specificity and accuracy. No established parameters are available for early and timely diagnosis. This study aims to address this gap by investigating the variability of blood plasma conductivity and dielectric constant using microwave probes previously validated for non-invasive glucose monitoring. The acquired data will be analyzed using the Anritsu VectorStar VNA to identify innovative and reliable parameters associated with the presence of severe infections.

CONDITIONS

Official Title

Sepsis and Hospital Mortality

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Cardiology patients without documented infection (Control Group)
  • Patients with sepsis
  • Patients with nosocomial infection
  • Patients with myocarditis, endocarditis, or pericarditis
  • Ability to provide written informed consent
Not Eligible

You will not qualify if you...

  • Severe or chronic medical conditions that may affect study results, such as autoimmune diseases, renal or hepatic failure
  • Use of medications like corticosteroids or immunosuppressants that could affect biophysical measurements
  • Diagnosis of cancer
  • Diseases affecting the immune system, including lymphomas and leukemias
  • Congenital or acquired immunodeficiencies such as HIV
  • Inability to read and sign the informed consent form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

''Annunziata'' Hospital

Cosenza, Italy, 87100

Actively Recruiting

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Research Team

A

Antonio Curcio, Medicine

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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