Actively Recruiting
Septum-guided Segmentectomy for Deep Early-stage Lung Cancer (SGS2512)
Led by Shanghai Chest Hospital · Updated on 2026-05-04
89
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the safety and effectiveness of a specialized surgical technique called "Septum-guided Segmentectomy" for treating early-stage lung cancer located deep within the lung tissue.Standard surgery for lung cancer often involves removing an entire lung lobe (lobectomy), which can significantly reduce a patient's breathing capacity. For small tumors, removing only a segment of the lung (segmentectomy) can preserve more healthy tissue. However, for tumors located deep in the lung, traditional segmentectomy is technically challenging and risks leaving cancer cells behind.In this study, surgeons will use the natural anatomical boundaries-the intersegmental veins and their surrounding thin membranes (septa)-as a guide to precisely remove the target lung segment. This "septum-guided" approach aims to ensure the cancer is completely removed while maximizing the preservation of healthy lung function.Participants will be followed for 3 years after surgery to monitor for cancer recurrence and assess their long-term recovery.
CONDITIONS
Official Title
Septum-guided Segmentectomy for Deep Early-stage Lung Cancer (SGS2512)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 80 years
- Clinical stage IA (cT1a-bN0M0) non-small cell lung cancer
- Tumor diameter 2 cm or smaller
- Solid-dominant lesion with consolidation-to-tumor ratio greater than 0.5
- Tumor located deep within the inner two-thirds of the lung on CT scans
- ECOG performance status of 0 or 1
- Pulmonary function with FEV1 and DLCO SB at least 60% of predicted
- Ability and willingness to provide written informed consent
You will not qualify if you...
- Multiple lung nodules or evidence of distant cancer spread
- Lymph node metastasis or pleural dissemination found during surgery
- Previous surgery on the same side of the lung
- History of other cancers within the past 5 years
- Severe heart or brain blood vessel diseases preventing surgery
- Pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Chest Hospital
Shanghai, Shanghai Municipality, China, 200030
Actively Recruiting
Research Team
J
Junfeng Gen, MD
CONTACT
Q
Qing Wang, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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