Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06514755

Sequential Genicular Nerve Ablation Prior to Geniculate Artery Embolization in Knee Pain

Led by Zagazig University · Updated on 2024-10-01

60

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate whether performing genicular nerve ablation (GNA) before geniculate artery embolization (GAE) improves pain relief and knee function in patients with chronic knee pain. The main questions it aims to answer are: * Does performing GNA prior to GAE enhance pain relief, as measured by the Visual Analog Scale (VAS), at 3 months post-procedure? * Does the sequential approach improve knee function as assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)? Study investigators will compare two groups to see if the sequential approach (GNA followed by GAE) provides better outcomes compared to GAE alone. Participants will: * Undergo either sequential GNA followed by GAE or GAE alone * Have their knee pain and function assessed at baseline, 1 month, 3 months, and 6 months post-procedure * Complete a structured patient satisfaction questionnaire (PSQ) at 3 months post-procedure * Be monitored for procedure-related adverse events up to 6 months post-procedure,

CONDITIONS

Official Title

Sequential Genicular Nerve Ablation Prior to Geniculate Artery Embolization in Knee Pain

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 80 years
  • Diagnosed with chronic knee pain not improved by conservative treatments
  • Able to provide informed consent
  • Willing to follow study procedures and attend follow-up visits
Not Eligible

You will not qualify if you...

  • Allergies to local anesthetics or active infection at the procedure site
  • Knee surgery within the last six months
  • Severe conditions like rheumatoid arthritis or other serious autoimmune diseases
  • Currently participating in another clinical trial that might affect study results

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zagazig University, Faculty of Medicine

Zagazig, Egypt, 44519

Actively Recruiting

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Research Team

A

Ahmed A Bessar, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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