Actively Recruiting

Age: 50Years - 85Years
FEMALE
NCT06164795

Sequential Therapies After Osteoanabolic Treatment

Led by 424 General Military Hospital · Updated on 2025-04-27

150

Participants Needed

8

Research Sites

179 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

12-month prospective, open-label, multicenter, international, observational study evaluating sequential treatments after osteoanabolics

CONDITIONS

Official Title

Sequential Therapies After Osteoanabolic Treatment

Who Can Participate

Age: 50Years - 85Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Postmenopausal women treated for severe osteoporosis who have completed romosozumab or teriparatide treatment
Not Eligible

You will not qualify if you...

  • Presence of bone diseases other than postmenopausal osteoporosis
  • Use of medications affecting bone metabolism other than romosozumab or teriparatide within 12 months prior to study entry
  • Creatinine clearance less than 60 mL/min/1.73 m2
  • Liver failure
  • Any type of cancer
  • Uncontrolled endocrine diseases
  • Serum 25-hydroxy vitamin D levels below 20 ng/mL (50 nmol/L)
  • Hypersensitivity to denosumab, zoledronate, teriparatide, romosozumab, or any excipients

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 8 locations

1

251 Airforce & VA General Hospital

Athens, Greece, 11525

Actively Recruiting

2

First Department of Propaedeutic and Internal Medicine, Medical School, National and Kapodistrian University of Athens

Athens, Greece, 11527

Actively Recruiting

3

, KAT General Hospital

Athens, Greece, 14561

Actively Recruiting

4

424 General Military Hospital

Thessaloniki, Greece, 56429

Actively Recruiting

5

Fondazione IRCCS Cà Granda-Ospedale Maggiore Policlinico

Milan, Italy

Actively Recruiting

6

Campus Bio-Medico University

Roma, Italy, 00128

Actively Recruiting

7

Department of Medicine, Surgery and Neurosciences, University of Siena

Siena, Italy, 53100

Actively Recruiting

8

University-Hospital S. Maria della Misericordia

Udine, Italy

Actively Recruiting

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Research Team

A

Athanasios D Anastasilakis, PhD

CONTACT

J

John Carey, Prof

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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