Actively Recruiting
Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation
Led by M.D. Anderson Cancer Center · Updated on 2026-02-19
80
Participants Needed
1
Research Sites
177 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To learn how radiation treatment may affect your responses to vaccines against pneumonia.
CONDITIONS
Official Title
Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients receiving, planning to receive, or recently completed chemoradiation for esophageal cancer with protons
- Patients receiving, planning to receive, or recently completed chemoradiation for esophageal cancer with intensity-modulated radiation therapy (IMRT)
- Patients receiving, planning to receive, or recently completed definitive proton therapy for unresectable hepatocellular carcinoma
- Patients receiving, planning to receive, or recently completed definitive IMRT for unresectable hepatocellular carcinoma
- Healthy age- and gender-matched individuals
- Patients of all genders, races, and nationalities
- Age over 18 years
- Ability to understand and willingness to sign a written informed consent document
You will not qualify if you...
- Patients with uncontrolled immunodeficiency such as HIV or previous/current immune suppressive therapy (except HIV patients on effective anti-retroviral therapy with undetectable viral load within 6 months)
- Patients receiving intravenous immunoglobulin (IVIG) during the study or in the three months prior
- Patients with psychiatric illness or social situations limiting compliance
- Individuals with pneumococcal vaccination in the last 5 years
- Individuals with severe allergy to any vaccine components
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
S
Steven H Lin, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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