Actively Recruiting
Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATs
Led by Ondokuz Mayıs University · Updated on 2026-05-04
60
Participants Needed
1
Research Sites
24 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to compare the analgesic effects of the serratus posterior superior intercostal plane block and intrathecal morphine in patients undergoing video-assisted thoracoscopic surgery. This is a prospective, randomized, controlled, single-center clinical trial including adult patients undergoing elective thoracoscopic surgery. Participants will be randomly assigned to receive either a serratus posterior superior intercostal plane block or intrathecal morphine before general anesthesia. The primary outcome is cumulative opioid consumption during the first 24 postoperative hours, expressed as intravenous morphine milligram equivalents. Secondary outcomes include pain scores, time to first analgesic request, quality of recovery, and postoperative complications. The study aims to determine whether these two techniques differ in their effectiveness for postoperative pain management.
CONDITIONS
Official Title
Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATs
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- American Society of Anesthesiologists physical status I to III
- Scheduled for elective video-assisted thoracoscopic surgery including wedge resection, segmentectomy, or lobectomy
You will not qualify if you...
- Refusal to participate
- Pregnancy
- Morbid obesity (body mass index greater than 40 kg per square meter)
- Allergy to opioids, local anesthetics, or nonsteroidal anti-inflammatory drugs
- Neuropsychiatric disorders, cognitive impairment, or inability to communicate
- History of substance abuse
- Use of anticoagulant therapy or presence of bleeding disorders
- Active systemic infection
- Severe cardiovascular, hepatic, renal, or endocrine disease
- Chronic pain syndrome or ongoing chronic pain treatment
- Emergency surgery or prior ipsilateral thoracic surgery
- Preoperative opioid use
- Significant intraoperative or postoperative bleeding or hemodynamic instability
- Requirement for prolonged postoperative mechanical ventilation longer than 18 hours
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Ondokuz Mayis University
Atakent, Samsun, Turkey (Türkiye), 55270
Actively Recruiting
Research Team
C
Cengiz Kaya, Prof Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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