C1q/TNF-related protein 3 (CTRP3) and 9 (CTRP9) concentrations are decreased in patients with heart failure and are associated with increased morbidity and mortality.
Chao Gao, Shasha Zhao, Kun Lian...
https://pubmed.ncbi.nlm.nih.gov/31182031Actively Recruiting
Age: 18Years - 85Years
All Genders
Healthy Volunteers
ID01372800
Serum Adiponectin Concentration, Activity and Isoforms in Chinese Population and Its Correlation to Cardiovascular and Cerebrovascular Diseases
Led by Xijing Hospital · Updated on 2025-02-07
30000
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying adiponectin, a protein involved in metabolism and protective against inflammation and ischemic injury, to understand its role as a potential risk factor for cardiovascular and cerebrovascular diseases in the Chinese population. This observational study follows participants for five years to explore the relationship between serum adiponectin levels, activity, isoforms, and the occurrence of heart and brain ischemia-related events. The study does not involve treatment interventions but monitors the natural course of participants' health, focusing on serum adiponectin concentration and its variants. During the five-year follow-up, participants will undergo regular assessments including blood tests for routine parameters, glucose, lipid profiles, and electrocardiograms to collect comprehensive data related to heart and brain health. Participants will be involved in scheduled evaluations to measure adiponectin levels and monitor for major adverse cardiovascular and cerebrovascular events over five years. The research team will track laboratory results, heart activity through ECG, and health outcomes to better understand the protein's influence. The study also includes monitoring for safety and adverse events, with participation lasting the full five years from enrollment.
CONDITIONS
Brief Title
Serum Adiponectin in Chinese Population and Its Correlation to Cardiovascular and Cerebrovascular Diseases
Who Can Participate
Age: 18Years - 85Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Available for 5 years of follow-up study
You will not qualify if you...
- Death caused by reasons other than cardiovascular and cerebrovascular diseases before study ends
- Floating population
- Pregnancy, lactation, or childbearing women
- Tumor
- Active liver disease or abnormal liver function with AST/ALT over 1.5 times normal
- Severe kidney dysfunction with serum creatinine over 3 mg/dl or 264 µmol/L
- Any condition that might increase risk of adverse events or abnormal labs as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Long-term Monitoring
Duration - 5 years
Participants are followed for 5 years to observe serum adiponectin concentration, activity and isoforms and their correlation to cardiovascular and cerebrovascular diseases.
Periodic visits over 5 years for blood tests, ECG, and health assessments
Trial Site Locations
Total: 1 location
1
Xijing Hospital
Xi'an, Shaanxi, China, 710032
Actively Recruiting
Loading map...
Research Team
L
Ling Tao, M.D Ph.D
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here