Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT07403331

Severe Chronic Neuropathic Pain: A Treatment Bundle, Using Spinal Cord Stimulation and Multidisciplinary Treatment, to Reduce Pain and Improve Physical Function.

Led by Oslo University Hospital · Updated on 2026-05-06

10

Participants Needed

1

Research Sites

60 weeks

Total Duration

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AI-Summary

What this Trial Is About

People with nerve damage can develop nerve pain. The pain can sometimes be severe and unpredictable, causing odd or alarming sensations - for example, lightning-like or electric shock feelings in the area served by the damaged nerve. The investigators will examine a treatment for nerve pain in the legs caused by nerve damage, which can occur after a herniated disc or a bone fracture, with or without surgery. Previous research suggests that spinal cord stimulation can relieve nerve pain in the legs after surgery or injury, but its effectiveness is still debated. Other studies show that multidisciplinary treatment helps people with long-term pain to improve their quality of life and to better cope in life. National and international guidelines recommend this kind of multidisciplinary care for long-term pain. There has yet been published research on spinal cord stimulation combined with multidisciplinary treatment as a bundle intervention. The investigators therefore want to find out whether this combined approach can reduce nerve pain in the legs and improve physical functioning.

CONDITIONS

Official Title

Severe Chronic Neuropathic Pain: A Treatment Bundle, Using Spinal Cord Stimulation and Multidisciplinary Treatment, to Reduce Pain and Improve Physical Function.

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Peripheral neuropathic pain in one or both legs for more than 6 months due to post spinal pain syndrome (type 1 or 2) or localized nerve damage
  • Neuropathic pain in the leg(s) is the dominant pain component
  • Age between 18 and 60 years
  • Previous standard conservative or surgical treatment attempted
  • Opioid use at implantation time less than 50 mg OMEQ daily
  • Willingness to actively participate in the treatment bundle
  • Living within reasonable travelling distance from Oslo
  • Proficiency in understanding spoken and written Norwegian
  • Cognitive ability to provide informed consent
  • Ability to operate the spinal cord stimulation system remote control
Not Eligible

You will not qualify if you...

  • Currently undergoing claims process for health benefits such as disability pensions from NAV
  • Psychological or psychiatric disorders that may affect treatment efficacy
  • Chronic generalized pain conditions
  • Other pain conditions in the affected area, such as osteoarthritis
  • Pregnancy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Department of pain management and research, Oslo university hospital

Oslo, Norway

Actively Recruiting

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Research Team

C

Christopher Ekholdt, PhD-student

CONTACT

L

Lars-Petter Granan, Ph.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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