Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
FEMALE
NCT07062367

Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy

Led by Tanta University · Updated on 2025-07-14

90

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will be conducted to evaluate the effects of different anesthetic modalities \[sevoflurane with or without intraoperative lidocaine infusion and Propofol total intravenous anesthesia (TIVA)\] on intracranial pressure (ICP) and cerebral oxygenation assessed by non-invasive methods during laparoscopic hysterectomy (LH).

CONDITIONS

Official Title

Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy

Who Can Participate

Age: 18Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age from 18 to 65 years.
  • American Society of Anesthesiologists (ASA) physical status I and II.
  • Body mass index (BMI) �35.
  • Females scheduled for laparoscopic hysterectomy.
Not Eligible

You will not qualify if you...

  • Patients' refusal to participate in the study.
  • Hypersensitivity and allergy to drugs of the study.
  • Contraindication for optic nerve sheath diameter assessment such as pre-existing ophthalmic diseases or history of ophthalmic surgery.
  • Any central nervous system or cardiovascular disease, severe hepatic or renal impairment.
  • Intraoperative inability to perform optic nerve sheath diameter measurement or conversion to open surgery.
  • If peak inspiratory pressure (PIP) exceeds 35.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tanta University

Tanta, El-Gharbia, Egypt, 31527

Actively Recruiting

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Research Team

E

Eman A Elrefaey, Master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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