Actively Recruiting
Sex Hormones Impact on Cannabis Response
Led by Maastricht University · Updated on 2026-02-18
21
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to systematically determine whether the cannabis response in human females is related to SH fluctuations throughout the menstrual cycle.
CONDITIONS
Official Title
Sex Hormones Impact on Cannabis Response
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biological female
- Used cannabis between 1 time a month and 2 times a week during the previous year
- Age between 18 and 40 years
- Free from psychotropic medication
- Free from hormonal birth control
- A regular menstrual cycle (last 3 cycles a duration between 21 and 35 days)
- Good physical health as determined by medical examination and laboratory analysis
- Absence of any major medical, endocrine and neurological condition as determined by medical examination and laboratory analysis
- Normal weight, body mass index (weight/height2) between 18 and 28 kg/m2
- Written Informed Consent
- Good knowledge and understanding of the English language
- Participants must be willing to refrain from taking illicit psychoactive substances during the study
- Participants must be willing to drink only alcohol-free liquids and no coffee, black or green tea, or energy drinks after midnight of the evening before the study session, as well as during the study day
- Participants must be willing not to drive a traffic vehicle or to operate machines within 24 h after substance administration
You will not qualify if you...
- History of drug addiction (determined by the medical questionnaire, drug questionnaire and medical examination)
- Pregnancy or lactation or pregnancy planned during study participation
- Hypertension (diastolic > 90 mmHg; systolic > 140 mmHg)
- Current or history of psychiatric disorder (determined by the medical questionnaire and medical examination)
- Current presence or history of psychosis in first-degree relatives
- Any chronic or acute medical condition
- History of cardiac dysfunctions (arrhythmia, ischemic heart disease, ...)
- Tobacco smoking (>20 per day)
- Excessive drinking (>20 alcoholic consumptions per week)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Maastricht University
Maastricht, Netherlands
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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