Actively Recruiting

Phase 4
Age: 60Years +
FEMALE
Healthy Volunteers
NCT03821857

Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

Led by Mayo Clinic · Updated on 2025-11-24

614

Participants Needed

2

Research Sites

565 weeks

Total Duration

On this page

Sponsors

M

Mayo Clinic

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.

CONDITIONS

Official Title

Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

Who Can Participate

Age: 60Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Women who previously participated in this study
  • Currently aged 60 years and older
  • More than six months post chemotherapy or major surgery requiring general anesthesia
  • Willing and able to sign informed consent
  • African American Women (for Mayo Clinic Jacksonville site only)
Not Eligible

You will not qualify if you...

  • Not able to read and speak English
  • In hospice care
  • Claustrophobic
  • If undergoing Tau imaging, cannot have QT prolongation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
+1

Trial Site Locations

Total: 2 locations

1

Mayo Clinic

Jacksonville, Florida, United States, 32224

Actively Recruiting

2

Mayo Clinic

Rochester, Minnesota, United States, 55905

Enrolling by Invitation

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Research Team

J

June Kendall-Thomas, CRC

CONTACT

D

Desirae Howe-Clayton, CRC

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease | DecenTrialz