Study of Sexual Function and Quality of Life in Women Undergoing LEEP or Colposcopy for HPV-Related Cervical Changes

What this Trial Is About

This research aims to understand how the loop electrosurgical excision procedure LEEP affects sexual function and quality of life in women with HPV-related cervical lesions. The study compares women undergoing LEEP to those who only have colposcopy visits, focusing on any changes in sexual function and health-related quality of life over time. The research is conducted across multiple centers and includes women referred for colposcopy due to cytological abnormalities or repeated HPV positivity. Participants are divided into two groups one receiving the LEEP treatment, which removes the affected cervical area using a small electric loop under local anesthesia, and a control group undergoing only colposcopy without LEEP. The study follows women over several years, with assessments planned at the first visit, then at 6 months, 24 months, 3 years, and 5 years after the initial procedure or colposcopy. During the study, participants complete web-based questionnaires about their sexual function using the Female Sexual Function Index FSFI and health-related quality of life using the 15D questionnaire. Researchers also collect background information from patient files and questionnaires. No additional visits or sample collections are required. The main outcomes measured are self-reported sexual function and quality of life scores over the follow-up period, with data securely managed and stored for analysis.

Sexual Function and Quality of Life After LEEP: a Prospective Multi-Center Study