Actively Recruiting
"Sexual Health Assessment of TinidaZole Against M. Genitalium (SHAZAM)"
Led by University of Washington · Updated on 2026-05-04
40
Participants Needed
1
Research Sites
57 weeks
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
H
Hologic, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective is to estimate the efficacy of tinidazole for the treatment of Mycoplasma genitalium (MG) among male patients who have been diagnosed with non-gonococcal urethritis (NGU) at the Public Health - Seattle \&King County (PHSKC) Sexual Health Clinic (SHC). Tinidazole was approved by the Food and Drug Administration (FDA) in May 2004 to treat other infections (i.e., trichomoniasis, giardiasis, amebiasis, bacterial vaginosis) but has not been systematically tested for effectiveness against M. genitalium. The dosing that the investigators are proposing does not significantly increase the risk associated with taking tinidazole and this investigation meets criteria for an IND exemption.
CONDITIONS
Official Title
"Sexual Health Assessment of TinidaZole Against M. Genitalium (SHAZAM)"
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Clinical diagnosis of non-gonococcal urethritis (NGU)
- Positive test for urogenital Mycoplasma genitalium within the prior 7 days
- Fluent in English
- Assigned male at birth
- Attending the Public Health - Seattle & King County Sexual Health Clinic
- Able to provide informed consent
- Able to complete a test of cure 21 days after finishing tinidazole treatment
You will not qualify if you...
- Known allergy to tinidazole
- Other reasons that make tinidazole unsafe as determined by the doctor
- Exclusion based on the clinician's discretion
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Harborview Medical Center, Public Health - Seattle & King County Sexual Health Clinic
Seattle, Washington, United States, 98104
Actively Recruiting
Research Team
L
Lisa Manhart, PhD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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