Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT03994510

SHame prOpensity in bOrderline Personality Disorder

Led by University Hospital, Montpellier · Updated on 2025-09-30

688

Participants Needed

1

Research Sites

571 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Montpellier

Lead Sponsor

I

INSERM 1061, " Neuropsychiatry: epidemiological and clinical research", Montpellier

Collaborating Sponsor

AI-Summary

What this Trial Is About

Borderline Personality Disorder (BPD) is a common psychiatric disorder occurring in 2 to 6% of the population. 70% of patients with BPD do at least one Suicide Attempt (SA) in their lives. It makes BPD the most related to SA condition. Negative interpersonal events are among the main stressor inducing a SA. Patients with BPD are characterized by emotional dysregulation, impulsivity (repeated parasuicidal and suicidal behaviors), and instability in interpersonal relationships. The feeling of shame related to this psychiatric disorder could be one of the causes of the high SA rate. In this study, patients with BPD will be follow-up during 5 years. The main objective is to study the propensity to feel shame as a predictor of SA. This include: * Study of shame propensity as a predictive factor of suicidal behavior - Identify homogeneous subgroups of patients with BPD based on SA, and overall functioning. * Identify biological markers predicting SA * Identify predictive and protective treatments (pharmacological and psychotherapeutic) for SA

CONDITIONS

Official Title

SHame prOpensity in bOrderline Personality Disorder

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be 18 years of age or older
  • Have a clinical diagnosis of Borderline Personality Disorder confirmed by SCID II
  • Have signed the informed consent form
  • Be able to understand the nature, purpose, and methods of the study
  • Be able to understand and complete clinical evaluations
Not Eligible

You will not qualify if you...

  • Being deprived of liberty by judicial or administrative decision
  • Being under legal guardianship or protected by law
  • Currently in an exclusion period due to participation in another study
  • Not affiliated with a social security scheme

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital of Montpellier

Montpellier, Hérault, France, 34295

Actively Recruiting

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Research Team

D

Déborah DUCASSE, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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