Actively Recruiting
Shock Energy for Electrical Cardioversion of Persistent Atrial Fibrillation
Led by Wellington Hospital · Updated on 2025-04-01
100
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the efficacy of a maximum output shock for cardioverting atrial fibrillation between two commonly used defibrillators in New Zealand . These machines have different maximum energy outputs, and to date no head-to-head comparison cardioverting atrial fibrillation between the two has been undertaken. The main question it aims to answer is whether either device is more likely to cardiovert patients referred for atrial fibrillation. Participants will be randomized to undergo cardioversion with one of two defibrillators at either 200J or 360J. Participants in each arm will undergo up to three shocks at the energy-level to which they have been randomized, using a standardized procedure. For participants randomized to the lower energy level who fail to return to normal rhythm after three shocks, they will be given a fourth shock at the higher energy level. All participants will then be asked to undertake a blood test the day following the cardioversion, and receive a follow up phone call. These are to ensure there is no difference in the safety of the procedure between the two energy levels. It is worth noting that these two components of the study (the blood test and phone call) are the only additional time commitment that is expected to be involved if you choose to participate in the study.
CONDITIONS
Official Title
Shock Energy for Electrical Cardioversion of Persistent Atrial Fibrillation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18
- Patients undergoing elective outpatient or non-emergent inpatient cardioversion for atrial fibrillation
- Eligible for anticoagulation
- Reliably anticoagulated for at least three weeks prior to cardioversion, or atrial fibrillation onset within 48 hours of cardioversion, or left atrial thrombus excluded on transoesophageal echocardiogram
- Able to provide consent for cardioversion and study participation
You will not qualify if you...
- Contraindication to anticoagulation
- Diagnosis of atrial flutter
- Need for emergent cardioversion
- Presence of implantable cardiac device such as pacemaker or implantable cardioverter defibrillator
- Unable to consent to cardioversion and/or study participation
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Wellington Regional Hospital
Wellington, Wellington Region, New Zealand, 6012
Actively Recruiting
Research Team
A
Allan M Plant, FRACP
CONTACT
D
Darren Hooks, FRACP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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