Actively Recruiting
Short-Term Atrial Pacing and Hemodynamics After Cardiac Surgery
Led by Saint-Joseph University · Updated on 2025-08-17
200
Participants Needed
1
Research Sites
60 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn whether temporary atrial pacing improves heart function after cardiac surgery under cardiopulmonary bypass (CPB). It will also help determine the best pacing rate during the first 24 hours after surgery. The main questions it aims to answer are: * Does atrial pacing improve cardiac output after surgery? * Is 70, 80, or 90 bpm the most effective pacing rate? * Does pacing reduce the risk of atrial fibrillation after surgery?
CONDITIONS
Official Title
Short-Term Atrial Pacing and Hemodynamics After Cardiac Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years or older
- Undergoing cardiac surgery with cardiopulmonary bypass including coronary artery bypass grafting, valve replacement or repair, or combined procedures
- Placement of epicardial atrioventricular pacing wires during surgery
- Placement of a Swan-Ganz catheter during surgery
- Signed informed consent
You will not qualify if you...
- Emergency surgery
- Having an internal pacemaker
- History of permanent atrial fibrillation
- Complete atrioventricular block upon weaning from cardiopulmonary bypass
- Junctional rhythm upon weaning from cardiopulmonary bypass
- Sinus rhythm less than 50 bpm upon weaning from cardiopulmonary bypass
- Failure of atrial or dual-chamber pacing (patients paced in ventricular mode VVI)
- Contraindication to Swan-Ganz catheter placement
- Hemodynamic instability defined by significant bleeding or tamponade requiring surgical re-intervention, or need for high doses of vasopressors (Norepinephrine > 1 mcg/kg/min, Dobutamine > 10 mcg/kg/min)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Anesthesia and Critical Care, Hôtel-Dieu de France Hospital
Beirut, Lebanon
Actively Recruiting
Research Team
R
Rhea Mattar
CONTACT
J
Joanna Tohme
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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