Short-Term Atrial Pacing to Improve Heart Function After Cardiac Surgery Using Cardiopulmonary Bypass A Randomized Study Comparing Different Pacing Rates 70, 80, 90 bpm During the First 24 Hours Post-Surgery

What this Trial Is About

Researchers are studying whether temporary atrial pacing improves heart function after cardiac surgery using cardiopulmonary bypass CPB. The trial focuses on whether atrial pacing enhances cardiac output, identifies the most effective pacing rate 70, 80, or 90 bpm, and examines if pacing lowers the risk of atrial fibrillation post-surgery. This evaluation is important as postoperative rhythm issues and reduced heart function frequently occur after such surgeries. Participants receive either continuous atrial pacing at 90 bpm or remain in their natural sinus rhythm during the first 24 hours after surgery. At four specific times arrival in ICU, 6, 12, and 24 hours post-surgery, transient pacing sequences at different rates 70, 80, and 90 bpm are applied briefly for 10 minutes each to measure heart function. This procedure is done in both groups to compare the effects of pacing and rate variations. During the study, participants are monitored using Swan-Ganz catheters to measure cardiac index and other heart function parameters at regular intervals within the first 24 hours post-surgery. Researchers also assess blood pressure, stroke volume, vascular resistance, and ventricular work. The study aims to determine the best pacing rate and whether pacing reduces atrial fibrillation risk, with careful safety monitoring throughout the postoperative period.

Short-Term Atrial Pacing and Hemodynamics After Cardiac Surgery