Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT05538416

Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional "Open" and Minimal Invasive Posterior Lumbar Interbody Fusion

Led by Jos M. A. Kuijlen · Updated on 2025-05-04

180

Participants Needed

1

Research Sites

167 weeks

Total Duration

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AI-Summary

What this Trial Is About

A combined prospective cohort study and retrospective analysis of previously collected data. Three different techniques for posterior lumbar interbody fusion (PLIF) are compared: CBT-PLIF, MI-PLIF and open PLIF. A total of 180 patients are included, who will be followed up to 6 weeks postoperatively.

CONDITIONS

Official Title

Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional "Open" and Minimal Invasive Posterior Lumbar Interbody Fusion

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 75 years
  • Diagnosis of degenerative or spondylolytic spondylolisthesis
  • Presence of neurogenic claudication and/or radicular leg pain
  • Low grade spondylolisthesis (Meyerding grade I or II)
  • Persistent symptoms for more than 3 months
Not Eligible

You will not qualify if you...

  • Previous spinal fusion surgery at the same spinal level
  • Osteoporosis (only if using bisphosphonate)
  • Active infection or history of infection at the surgical site
  • Active cancer
  • Spondylolisthesis grade III or higher
  • More than one symptomatic spinal level requiring fusion
  • Pregnancy
  • Contraindication to surgery
  • Severe mental or psychiatric disorders
  • Substance abuse
  • Insufficient knowledge of the Dutch language
  • Morbid obesity with body mass index over 40

AI-Screening

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Trial Site Locations

Total: 1 location

1

UMCG

Groningen, Netherlands, 9713 GZ

Actively Recruiting

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Research Team

D

Diane H. Steenks

CONTACT

H

Hui Ling Li, BsC

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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