Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
All Genders
ID07483788

Short Term Outcome of Complete Pulpotomy Using MTA vs Biodentine in Symptomatic Irreversible Pulpitis - A Randomized Controlled Trial

Led by Dow University of Health Sciences · Updated on 2026-03-19

60

Participants Needed

2

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the short-term outcomes of complete pulpotomy treatments using two different materials, Mineral Trioxide Aggregate (MTA) and Biodentine, in patients with symptomatic irreversible pulpitis. This trial aims to compare these treatments to understand their effects on pain and healing in affected molar teeth. The study is a randomized controlled trial conducted by Dow University of Health Sciences, focusing on adults aged 18 to 40 years with moderate to severe tooth pain. The treatment involves two visits performed by a single dentist. Initially, patients receive a local anesthetic to prevent discomfort, and a rubber sheet is used to keep the area clean. The dentist removes the decayed part of the tooth and infected tissue, controls bleeding, and places either MTA or Biodentine inside the tooth. A temporary filling is applied, followed by a final filling in the next visit. X-rays are taken to assess the treatment results. Patients may take ibuprofen as needed for pain and attend follow-ups at 1 day, 1 week, 1 month, and 3 months to monitor healing. Participants will undergo initial assessments including medical and dental history, pain rating on a scale of 1 to 10, sensitivity tests like cold and electric pulp tests, and X-rays. After treatment, the healing process is regularly checked through follow-up visits and imaging. The primary outcome is the short-term success of the pulpotomy over three months. Patients are monitored closely to ensure proper healing and pain management throughout the study period.

CONDITIONS

Brief Title

Short Term Comparative Assessment of MTA and Biodentine in Complete Pulpotomy for Symptomatic Irreversible Pulpitis

Who Can Participate

Age: 18Years - 40Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 40 years, both males and females
  • Carious exposed maxillary and mandibular molar teeth
  • Moderate to severe pain rated 4 to 10 on the visual analog scale
  • Diagnosed with symptomatic irreversible pulpitis by cold test and electric pulp test
  • Periapical index of 1
  • Hemostasis achieved within 10 minutes after full pulpotomy
Not Eligible

You will not qualify if you...

  • Any traumatic injury to the tooth
  • Non-restorable carious lesion
  • Immature or open root apices
  • Internal or external root resorption
  • Calcified canals

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Short term, up to 3 months

Participants receive a complete pulpotomy using either MTA or Biodentine as the pulpotomy material.

1 treatment visit and follow-up visits during 3 months

Trial Site Locations

Total: 2 locations

1

Dr Khadija Zubair

Karachi, Sindh, Pakistan

Actively Recruiting

2

Dr Khadija Zubair

Karachi, Sindh, Pakistan

Actively Recruiting

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Research Team

D

Dr Khadija Zubair, Postgraduate trainee- FCPS

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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