Actively Recruiting
Short-Term Effects of Antihypertensive Drugs on Postural Balance and Fall Risk
Led by Abant Izzet Baysal University · Updated on 2026-02-12
186
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the short-term effects of three commonly prescribed antihypertensive drug classes (beta-blockers, ACE inhibitors, and calcium channel blockers) on postural balance and fall risk in adults with newly diagnosed primary hypertension. The main questions it aims to answer are: * Do different antihypertensive drugs affect objective balance performance and fall risk? * What are the effects of these medications on dizziness and fear of falling? Researchers will use a balance analysis system (Biodex Balance System) and self-reported scales (Dizziness Handicap Inventory and Falls Efficacy Scale) to assess outcomes. Participants will: * Be randomly assigned to one of three drug groups (metoprolol, ramipril, or amlodipine) * Be evaluated at baseline (prior to treatment), at 2 weeks, and at 4 weeks after starting treatment * Complete balance tests and questionnaires at each time point This study aims to provide clinical insight into how commonly used blood pressure medications may impact balance and fall risk in real-world settings.
CONDITIONS
Official Title
Short-Term Effects of Antihypertensive Drugs on Postural Balance and Fall Risk
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 and 75 years
- Newly diagnosed with primary hypertension
- No prior use of antihypertensive medication
- No history of neurological, vestibular, orthopedic, or psychiatric conditions affecting balance
- Able to walk independently without assistive devices
- Provided written informed consent to participate in the study
You will not qualify if you...
- Secondary hypertension
- Known diagnosis of vestibular disorders (e.g., BPPV, Ménière's disease)
- Use of medications that may affect balance (e.g., sedatives, psychotropic drugs)
- History of falls due to trauma unrelated to balance
- Cognitive impairment preventing proper test participation
- Inability to complete the assessments at follow-up timepoints (2nd and 4th week)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Bolu Abant Izzet Baysal University, Izzet Baysal Training and Research Hospital
Bolu, Turkey (Türkiye), 14030
Actively Recruiting
Research Team
A
Alp Ozel, PT, PhD
CONTACT
U
Umut A Ugras, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here