Caffeine content in filter coffee brews as a function of degree of roast and extraction yield.
Zachary R Lindsey, Joshua R Williams, James S Burgess...
https://pubmed.ncbi.nlm.nih.gov/39582028Actively Recruiting
Phase Not Applicable
Age: 18Years - 35Years
All Genders
Healthy Volunteers
ID07024940
Acute Effects of Coffee, Anthocyanin-Caffeine Supplement and Placebo on Exercise Performance Markers
Led by St. Louis University · Updated on 2025-08-19
12
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how a commercial pre-workout supplement containing anthocyanins and caffeine, coffee, and water affect exercise performance. The study focuses on healthy adults aged 18 to 35 who regularly engage in resistance or aerobic exercise. This research aims to understand which drink may improve physical and cognitive performance during exercise testing. It is conducted by St. Louis University and involves multiple exercise assessments. Participants will attend four lab visits. The first visit assesses eligibility and fitness levels. Then, during three separate testing visits spaced at least three days apart, each participant will consume one of three beverages: a specially brewed Ethiopian coffee, an anthocyanin-caffeine pre-workout supplement, or water as a placebo. The beverage is consumed 45 minutes before testing, followed by a warm-up and rest period. The testing includes a 1-mile treadmill run at an incline with self-selected speed, a Wingate cycle ergometer test involving a 30-second all-out effort, and an agility reaction time test using light-up buttons. Throughout the study, participants will be evaluated on anaerobic power, treadmill running time, and reaction time after each drink. Researchers will monitor performance changes to compare the effects of the three beverages. The study includes regular assessments, and participants will complete all tests under controlled conditions. The total participation spans multiple visits over several weeks, allowing for thorough measurement of the short-term effects of these drinks on exercise performance.
CONDITIONS
Brief Title
Short-term Effects of Caffeine and a Multi-ingredient Pre-workout on Exercise Performance
Who Can Participate
Age: 18Years - 35Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Healthy male or female adults aged 18 to 35 years old
- Regularly engaged in resistance training or aerobic exercise at least 3 times per week, at least 30 minutes per session for the past 6 months
- Able to provide written informed consent
You will not qualify if you...
- History or current diagnosis of cardiovascular or metabolic diseases such as diabetes, prediabetes, hypertension, arrhythmia, heart attack, stroke, non-alcoholic fatty liver disease, or chronic kidney disease
- History of seizure disorder
- Currently taking prescription medications including beta-blockers, antidepressants, anti-anxiety drugs, or pain killers
- Currently pregnant, breastfeeding, pregnant within the past year, or at risk of pregnancy
- Recent participation in another clinical trial
- Sensitivities or allergies to caffeine, coffee, berries, maltodextrin, monk fruit extract, or other known food allergies
- Currently undertaking serious exercise training of 6 or more days per week
- Recently started daily creatine or beta-alanine supplementation within the past 3 months (consistent use for more than 3 months is allowed)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Testing Visits
Duration - 4 weeks
Participants attend three separate lab visits where they consume one of the assigned beverages—pre-workout supplement, Ethiopian coffee, or placebo—and then perform exercise tests including a 1-mile treadmill run, a Wingate cycle ergometer test, and an agility reaction time test.
3 visits (in-person)
Trial Site Locations
Total: 1 location
1
Saint Louis University
St Louis, Missouri, United States, 63103
Actively Recruiting
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Research Team
D
Dylan Moffatt, Bsc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
3
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Published Research Related To This Trial
The Effect of Pre-Exercise Hyperhydration on Exercise Performance, Physiological Outcomes and Gastrointestinal Symptoms: A Systematic Review.
William T Jardine, Brad Aisbett, Monica K Kelly...
https://pubmed.ncbi.nlm.nih.gov/37490269Voluntary drinking behaviour, fluid balance and psychological affect when ingesting water or a carbohydrate-electrolyte solution during exercise.
Oliver J Peacock, Dylan Thompson, Keith A Stokes
https://pubmed.ncbi.nlm.nih.gov/21986184The effect of pre-exercise carbohydrate supplementation on anaerobic exercise performance in adolescent males.
Jonah D Lee, Lauren E Sterrett, Lisa M Guth...
https://pubmed.ncbi.nlm.nih.gov/21881155Effects of Pre-Workout Multi-Ingredient Supplement on Anaerobic Performance: Randomized Double-Blind Crossover Study.
Piotr Kaczka, Amit Batra, Katarzyna Kubicka...
https://pubmed.ncbi.nlm.nih.gov/33182295