Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
FEMALE
NCT07095569

Shoulder Denervation for Post Mastectomy Irradiation Shoulder Pain

Led by National Cancer Institute, Egypt · Updated on 2026-05-13

60

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Breast cancer is the second most common cancer world-wide following lung cancer. It afflicts about 1.7 million patients annually, of which 60% mandate surgery of the breast and/or the axilla, and nearly 20-50% of them may develop post mastectomy pain syndrome . After breast cancer surgery, between 6% and 86% of people may develop tight bands of fibrous tissue under their skin, known as axillary web syndrome. These bands can cause pain in the shoulder area by trying to raise or extend the arm. Shoulder pain is a common side effect of breast cancer surgery and treatment. Various medical and interventional procedures have been tried for treating postmastectomy shoulder pain, with varying efficacy . Among the interventional procedures that may have a role for treatment. Innervation of the glenohumeral joint (GHJ) can be divided into anterior and posterior innervation from articular branches of the suprascapular nerve (SN):C5 \&6 (posterior-lateral), axillary nerve (AN):C5 \&6 (anterior-lateral, inferior, and posteriorlateral), and lateral pectoral nerve (LPN): C5 \&6 (anterior superior)

CONDITIONS

Official Title

Shoulder Denervation for Post Mastectomy Irradiation Shoulder Pain

Who Can Participate

Age: 18Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • ASA physical status II or III
  • Patients with post mastectomy irradiation shoulder pain
  • Body mass index (BMI) between 20 and 40 kg/m2
Not Eligible

You will not qualify if you...

  • Patient refusal to participate
  • Known sensitivity or contraindication to study medications
  • Pregnancy
  • Recent myocardial infarction
  • Hemodynamically unstable condition
  • Local or systemic infection (sepsis)
  • Psychiatric illness

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National Cancer institute

Cairo, Cairo Governorate, Egypt, 002

Actively Recruiting

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Research Team

S

suzan Adlan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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