Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06886477

Sickle Cell, Pain and Mediterranean Diet

Led by University of Illinois at Chicago · Updated on 2026-04-02

30

Participants Needed

1

Research Sites

87 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet.

CONDITIONS

Official Title

Sickle Cell, Pain and Mediterranean Diet

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of sickle cell disease
  • Chronic non-vaso-occlusive pain experienced on average 3 or more days per week for more than 6 months
  • Ability to speak, read, write, and understand English
  • Mediterranean Eating Pattern for Americans (MEPA-III) score less than 13, showing they do not currently follow a Mediterranean diet
Not Eligible

You will not qualify if you...

  • Taken systemic antimicrobials to treat an infection within the last 4 weeks
  • History of colon cancer or inflammatory bowel disease
  • History of Clostridium difficile infection in the past 12 weeks
  • Unable to maintain current physical activity level during the study
  • Currently following a Mediterranean diet, vegan diet, or have dietary restrictions preventing Mediterranean diet use
  • Lack access to a safe space to store and reheat food
  • Living in a facility that provides meals
  • Pregnant or breastfeeding
  • More than 7 inpatient hospital stays in the past year
  • Currently receiving dialysis treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Illinois Chicago

Chicago, Illinois, United States, 60612

Actively Recruiting

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Research Team

L

Lisa Tussing-Humphreys, PhD, MS, RD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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