Actively Recruiting
Simplification of Oral Sodium Loading Test in the Diagnosis of Primary Aldosteronism: 2-day Replacing 3-day Method
Led by Peking Union Medical College Hospital · Updated on 2024-12-27
33
Participants Needed
1
Research Sites
53 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To compare the consistency of 24-hour urinary aldosterone in the diagnosis of primary aldosteronism by oral sodium loading test between the second day method and the third day method
CONDITIONS
Official Title
Simplification of Oral Sodium Loading Test in the Diagnosis of Primary Aldosteronism: 2-day Replacing 3-day Method
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with hypertension and hypokalemia diagnosed with primary aldosteronism according to latest guidelines
- Age between 20 and 70 years, male and female
- Body mass index between 18.5 and 23.9 kg/m2
- For healthy volunteers: blood pressure 90-120/60-80 mmHg on three consecutive office readings
- For healthy female volunteers: regular menstrual cycle and blood/urine samples taken during non-menstrual period
- Regular dietary habits
- No medications taken within the past month
You will not qualify if you...
- Endocrine hypertension causes other than primary aldosteronism, such as pheochromocytoma or Cushing syndrome
- Renal artery stenosis or low potassium due to renal tubular acidosis, Bartter syndrome, Gitelman syndrome, or other factors
- History of hyperthyroidism, liver or kidney insufficiency, malignant tumors, metabolic diseases, cardiovascular or mental disorders, menstrual disorders
- For healthy volunteers: history of hypokalemia, liver or kidney dysfunction, malignant tumors, metabolic or cardiovascular diseases, psychiatric disorders
- Menstrual irregularities or use of contraceptive pills
- History of hypertension
- Use of anti-inflammatory drugs, potassium diuretics, or special health products within 4 weeks prior to examination
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100010
Actively Recruiting
Research Team
T
Tong Anli
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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