Actively Recruiting

Age: 18Years +
All Genders
NCT05717842

Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates

Led by Indiana University · Updated on 2026-03-12

15

Participants Needed

1

Research Sites

164 weeks

Total Duration

On this page

Sponsors

I

Indiana University

Lead Sponsor

J

Jerome A. Josephs Fund for Transplant Innovation Fund

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of the study is to determine how much a persons kidney function recovers after receiving a simultaneous liver kidney transplant. The investigators will be contacting patients with kidney dysfunction with estimated GFR between 25 and 40 (not on dialysis treatment) who are listed to receive a simultaneous liver kidney (SLK) transplant to look at this function recovery. The investigators hope to develop a criteria based on GFR measurement, kidney function calculations from native kidneys vs transplanted kidney and compare the contributions, and correlate with estimated GFR on basic metabolic panel (BMP: a blood test) to predict higher chances of recovery of native kidney function.

CONDITIONS

Official Title

Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years old or older
  • Listed for liver transplant for end-stage liver disease and kidney transplant (not on dialysis at time of transplant surgery)
  • Have two native kidneys
  • Willing to participate and sign informed consent form
Not Eligible

You will not qualify if you...

  • Unstable patients (e.g., in ICU or on continuous renal replacement therapy who cannot complete the nuclear medicine scan or those with acute kidney injury on hemodialysis)
  • Prior history of any solid organ transplant
  • Currently pregnant or breastfeeding
  • History of autosomal dominant polycystic kidney disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IU Health University Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

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Research Team

M

Mary Balmes-Fenwick, B.S.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates | DecenTrialz