Actively Recruiting
Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC)
Led by Zealand University Hospital · Updated on 2026-04-02
100
Participants Needed
5
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
People who have undergone curative surgery for non-small cell lung cancer (NSCLC) often experience reduced quality of life (QoL), a high burden of symptoms, and physical deconditioning. Current Danish rehabilitation offers are heterogeneous and inconsistent and not tailored to the specific needs of this population. Additionally, some patients continue to suffer from persistent physical symptoms months or even years after surgery, yet no targeted support is currently available for them. Singing - delivered as a structured form of training - has shown benefits in improving both physical and psychological outcomes in individuals with chronic obstructive pulmonary disease (COPD). Although singing has not yet been studied in NSCLC patients, the two conditions share overlapping symptoms and characteristics. Therefore, the present study aims to explore whether a singing-based intervention can help reduce symptom burden and improve physical function and QoL in NSCLC patients 6 to 18 months post-surgery. To test this, a multi-centre randomised controlled trial (RCT) will be conducted, comparing a singing intervention to usual care. Given that travel and distance often pose significant barriers to participation, the intervention will be delivered online.
CONDITIONS
Official Title
Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Persistent symptoms 6-18 months after surgical resection of localized lung cancer by video-assisted thoracoscopy (VATS)
- Symptom score indicating clinically relevant problems needing healthcare attention
- Surgery for stage I lung cancer done 6-18 months earlier
- Motivated to participate and accept randomization
- Access to computer or tablet with internet
- Ability to speak and understand Danish
- Willingness to attend singing sessions twice a week as scheduled
You will not qualify if you...
- Unstable coronary diseases
- Severe cognitive disabilities such as dementia
- Need for additional chemotherapy or other cancer therapies
- Signs of lung cancer recurrence on follow-up CT scans
AI-Screening
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Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
August Krogh Section for Molecular and Human Physiology, Department of Nutrition, Exercise, and Sports, Faculty of Health and Medical Sciences, University of Copenhagen
Copenhagen, Denmark, 2100
Actively Recruiting
2
Department of Respiratory Medicine, Bispebjerg Hospital
Copenhagen, Denmark, 2400
Actively Recruiting
3
Department of Medicine Roskilde and Næstved, Zealand University Hospital
Næstved, Denmark, 4700
Actively Recruiting
4
Department of Respiratory Medicine, Odense University Hospital
Odense, Denmark, 5000
Actively Recruiting
5
Department of Respiratory Medicine, Lillebaelt Hospital
Vejle, Denmark, 7100
Actively Recruiting
Research Team
M
Mette Kaasgaard, PhD
CONTACT
U
Uffe Bødtger, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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