Effects and Mechanisms of Online Delivered Singing Training vs Usual Care in Patients With Persistent Symptoms 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC) - a Multi-centre RCT

What this Trial Is About

Researchers are investigating whether an online singing training program can improve physical function, reduce symptoms, and enhance quality of life in people who have undergone surgery for non-small cell lung cancer (NSCLC) six to eighteen months earlier. This study compares singing training to usual care in a multi-center randomized controlled trial. Singing has shown benefits in respiratory diseases like COPD, which shares symptoms with NSCLC, and this study aims to see if similar benefits apply to lung cancer patients. Participants will be randomly assigned to either a 10-week online singing training program based on the Singing for Lung Health (SLH) approach or to usual care followed by singing training after the initial period. The singing sessions are held twice a week for 1.5 hours, delivered by trained singing teachers, and include physical warm-ups, vocal exercises, singing, movement, and playful activities. Participants may also continue other physical or singing activities during the study. During the trial, participants will be assessed before and after the 10-week intervention period using measures such as the Six Minute Walking Test, perceived exertion, quality of life questionnaires, and symptom burden evaluations. Researchers will monitor changes in physical capacity, breathlessness, anxiety, depression, and other health-related outcomes. Adherence and any adverse events will be recorded. The study is expected to run from early 2026 to late 2027, with multiple follow-up assessments for participants.

Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC)