Actively Recruiting

Phase 1
Age: 18Years - 70Years
All Genders
NCT06954558

A Single-Arm, Open-Label, Phase I Study of GK01 for Advanced Solid Tumor

Led by Tianjin Medical University Cancer Institute and Hospital · Updated on 2025-05-01

15

Participants Needed

1

Research Sites

174 weeks

Total Duration

On this page

Sponsors

T

Tianjin Medical University Cancer Institute and Hospital

Lead Sponsor

B

Beijing Geekgene Technology Co., LTD

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is a Phase I, open-label, single-arm clinical trial to evaluate the safety, pharmacokinetics, and preliminary efficacy of GK01 in patients with advanced solid tumors.

CONDITIONS

Official Title

A Single-Arm, Open-Label, Phase I Study of GK01 for Advanced Solid Tumor

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to understand and sign a written informed consent document
  • Age between 18 and 70 years, male or female
  • Histopathologically confirmed advanced solid tumor with failure or intolerance to standard treatment
  • At least one resectable tumor lesion without prior radiation or local therapy
  • At least one measurable lesion at baseline per RECIST version 1.1
  • Expected survival time of more than 12 weeks
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
  • Adequate organ functions
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Tianjin Medical University Cancer Institute & Hospital

Tianjin, China

Actively Recruiting

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Research Team

J

Jihui Hao

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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