Actively Recruiting
Single Dose Amikacin for Uncomplicated Cystitis in the ED: A Feasibility Study
Led by Antonios Likourezos · Updated on 2026-03-04
75
Participants Needed
1
Research Sites
223 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to determine if a single dose of amikacin (a type of antibiotic) can be used to effectively treat emergency department patients with uncomplicated cystitis (inflammation of the bladder). Participating in this study will allow the patient to treat their urinary tract infection (UTI) with a single intramuscular (IM (into the arm)) or intravenous (IV (into the vein)) shot of amikacin, rather than having to go to the pharmacy to pick up a prescription for antibiotics, and then take antibiotics for 3-7 days. A single dose of amikacin has been demonstrated to be safe, effective and well tolerated in other studies, but some patients may decline to participate because they do not wish to have an IV or IM shot, or because they don't want to speak on the phone with a research assistant three times over the next 30 days.
CONDITIONS
Official Title
Single Dose Amikacin for Uncomplicated Cystitis in the ED: A Feasibility Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female emergency medicine patients
- Age 14 years or older
- Diagnosed with uncomplicated urinary tract infection
- Presenting with a primary urinary complaint and nitrite-positive urine
You will not qualify if you...
- Pregnant
- Abnormal genitourinary tract
- Recent urinary tract instrumentation
- Immunosuppression
- Creatinine clearance less than 25 mL/min
- Signs of pyelonephritis or sepsis
- Antibiotic treatment within the past 30 days
- Unavailable for phone follow-up at 3, 7, and 30 days
- Requires hospital admission
- Abnormal mental status
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Maimonides Medical Center
Brooklyn, New York, United States, 11219
Actively Recruiting
Research Team
R
Reuben Strayer, MD
CONTACT
A
Antonios Likourezos, MA, MPH
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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