Actively Recruiting

Age: 18Years +
All Genders
NCT07337629

Single Dose Preemptive Paracetamol or Ibuprofen Before Septrorhinoplasty on Intra- and Postoperative Opioid Consumption.

Led by Samsun University · Updated on 2026-01-13

54

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Reducing intra- and postoperative pain or using less opioids is an essential strategy in today's operations. One emerging and widely used method in this context is the use of preemptive analgesic medication. Paracetamol and ibuprofen used preemptively have been shown to reduce postoperative opioid use and pain scores. There are also studies showing that preemptive analgesia with different analgesic medications reduces opioid consumption and postoperative pain. Our study will evaluate both the intraoperative and postoperative effectiveness of paracetamol and ibupurofen with preemptive analgesia, considering total opioid use. It will also investigate drug side effects and their advantages using a 15-question compilation quality scale, validated in Turkish.

CONDITIONS

Official Title

Single Dose Preemptive Paracetamol or Ibuprofen Before Septrorhinoplasty on Intra- and Postoperative Opioid Consumption.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Undergoing septorhinoplasty surgery
  • ASA physical status 1 or 2
  • Men and women aged 18 to 65 years
  • Able and willing to provide informed consent and participate in the study
Not Eligible

You will not qualify if you...

  • ASA physical status 3 or 4
  • Under 18 years of age
  • Serious kidney, liver, heart, or lung diseases
  • Allergy to paracetamol or ibuprofen
  • Bleeding disorders, platelet dysfunction, gastrointestinal disease, or peptic ulcer
  • Pregnancy, planning pregnancy, or breastfeeding
  • Use of aspirin or other anticoagulant medications

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Samsun University Samsun Training and Research Hospital

Samsun, Turkey (Türkiye)

Actively Recruiting

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Research Team

H

Hasan Cetinkaya, M.D.

CONTACT

C

Caner Genc, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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