Actively Recruiting
Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer
Led by Roswell Park Cancer Institute · Updated on 2026-04-30
1500
Participants Needed
3
Research Sites
417 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This phase II trial studies how well single-fraction stereotactic body radiation therapy (SBRT) works when compared to standard radiation therapy in treating patients with cancer that has spread to other places in the body (metastatic). Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method can kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue.
CONDITIONS
Official Title
Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pathologically confirmed malignancy
- Clinical or pathologic evidence of metastatic disease
- Presence of a malignant site causing symptoms or expected to cause symptoms where radiation may help
- Use of adequate birth control for participants who can have children
- Control of other primary cancers or confirmation that the metastatic site is the target
- Willingness and ability to follow study procedures including surveys and assessments
- Understanding of the investigational study and signed informed consent
You will not qualify if you...
- Previous radiation therapy to the planned treatment area
- Known brain metastases
- Pregnancy or nursing
- Inability to accurately report pain medication use
- Need for surgery or metastasectomy at the planned radiation site
- Severe active health problems like recent heart failure, heart attack, serious infections, or respiratory illness
- Unwillingness or inability to follow study requirements
- Conditions preventing safe study participation as judged by the investigator
- Adults unable to consent
- Participants under 18 years old
- Prisoners
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Actively Recruiting
2
The Cancer Institute at St. Francis Hospital
East Hills, New York, United States, 11548
Actively Recruiting
3
Good Samaritan Hospital
West Islip, New York, United States, 11795
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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