Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06668766

Single Lumen Midline Catheter vs Long Peripheral Intravenous Cather for Difficult Intravenous Access in the ED

Led by Albany Medical College · Updated on 2026-01-20

270

Participants Needed

1

Research Sites

146 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Many patients in the emergency department have veins that are difficult to get an intrevenous (IV) catheter into (called "difficult IV access"). These patients may require other methods to obtain access to a vein for administration of the necessary medications. The 2-inch long IV is most commonly used in emergency departments for people with difficulty IV access. Typically, a healthcare worker will use an ultrasound to help to see the veins underneath the skin while inserting the IV into the vein. That is, the ultrasound helps the healthcare worker visualize veins that are deeper in the arm and may not be felt through the skin. Another device that can be used is a 4-inch midline catheter. This device is less commonly used as many emergency departments do not have participants available, but it serves the same purpose as the 2-inch long IVs (that is, to give medicine into the vein and sometimes to take blood). A 4-inch midline catheter is similar to a 2-inch long IV, but has a few differences. First, the 4-inch midline catheter is even longer than the 2-inch long IV. The 4-inch midline catheter is 10-cm (about 4-inches or the size of 4 quarters side-by-side), while the 2-inch long IV is 4.78-cm (nearly 2-inches or two quarters side-by-side). Second, the 4-inch midline catheter is inserted into using a guidewire to help move the catheter in the vein (similar in concept to a train moving along a track), while the 2-inch long IV does not have this guidewire. The guidewire does not hurt and most do not know it is being used. It is just an additional step to help guide the catheter in the vein. The investigators are conducting this research study to determine which catheter is better for patients with difficult IV access: the 4-inch midline catheter or the 2-inch long IV.

CONDITIONS

Official Title

Single Lumen Midline Catheter vs Long Peripheral Intravenous Cather for Difficult Intravenous Access in the ED

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 years or older presenting to the emergency department with difficult IV access
  • Difficult IV access defined by either two failed attempts at IV insertion by qualified emergency staff or self-reported history of difficult IV access with previous multiple IV attempts
  • History of requiring rescue devices after failed IV attempts including ultrasound-guided IV, midline catheter, peripherally inserted central catheter, central venous catheter, or intraosseous catheter
  • History or current conditions known for difficult IV access such as implanted port device, end stage renal disease with fistula, sickle cell disease, or intravenous drug use
Not Eligible

You will not qualify if you...

  • Patients under 18 years of age
  • Known prisoners
  • Non-English-speaking patients
  • Patients unable to provide written consent or lacking capacity to consent
  • Patients with tissue or treatment conditions preventing device stabilization in available extremities (e.g., burns, complex fractures, dialysis fistulas)
  • Patients without identifiable target veins by ultrasound
  • Known pregnant patients
  • Previously enrolled or withdrawn from this study
  • Patients presenting when study IV proceduralists are unavailable
  • Patients for whom study participation would delay urgent medical care

AI-Screening

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Trial Site Locations

Total: 1 location

1

Albany Medical Center Hospital

Albany, New York, United States, 12054

Actively Recruiting

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Research Team

A

Alexander Bracey, MD

CONTACT

M

Michael J Waxman, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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