Actively Recruiting

Phase Not Applicable
Age: 18Years - 50Years
FEMALE
NCT07171684

Single vs Multi-Dose Insulin for Glycemic Control (SUGAR)

Led by Rutgers, The State University of New Jersey · Updated on 2026-04-16

176

Participants Needed

2

Research Sites

76 weeks

Total Duration

On this page

Sponsors

R

Rutgers, The State University of New Jersey

Lead Sponsor

N

NYU Langone Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to see if diabetes in pregnancy can be treated with once daily dosing of insulin instead of once daily dosing plus insulin with meals. The main question this study aims to answer is: 1. Can a once daily dose of long-acting insulin control blood sugars as well as long-acting insulin plus meal-time insulin? 2. Do babies born to mothers who take one dose of long-acting insulin have more complications after birth than babies born to mothers who take long-acting and meal-time insulin? Researchers will compare one dose of long-acting insulin per day to this plus three doses of short-acting insulin with each meal to see if blood sugars are controlled. Participants will send their blood sugar logs to the study staff weekly, instead of to their OB/GYN, for adjustments to their insulin dosing.

CONDITIONS

Official Title

Single vs Multi-Dose Insulin for Glycemic Control (SUGAR)

Who Can Participate

Age: 18Years - 50Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with type 2 diabetes mellitus or A2 gestational diabetes mellitus requiring insulin use during pregnancy
  • Aged between 18-50
  • Speak English or Spanish
Not Eligible

You will not qualify if you...

  • Pre-existing use of insulin
  • Gestational age greater than or equal to 35 weeks 0 days
  • Planning to follow-up with a doctor not associated with RWJ Barnabas or NYU Langone Health and/or deliver at a hospital other than RWJUH or NYU
  • Unwilling or unable to upload or email weekly blood sugar logs
  • Contraindication to Lispro or Lantus insulin, or patient chooses not to use insulin therapy
  • Fetal anomaly present

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Robert Wood Johnson Univeristy Hospital

New Brunswick, New Jersey, United States, 08901

Actively Recruiting

2

Maternal-Fetal Medicine at NYU Langone Obstetrics & Gynecology Associates

New York, New York, United States, 10022

Not Yet Recruiting

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Research Team

M

Morgan Dunn, MD

CONTACT

E

Emily Rosenfeld, DO

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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