Actively Recruiting
Single-port Versus Conventional Laparoscopic Surgery for Radical Proximal Gastric Cancer: A Randomized Controlled Trial
Led by First Affiliated Hospital of Wenzhou Medical University · Updated on 2026-05-14
90
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the safety and efficacy of SP1000 and conventional laparoscopy in radical gastrectomy for proximal gastric cancer.
CONDITIONS
Official Title
Single-port Versus Conventional Laparoscopic Surgery for Radical Proximal Gastric Cancer: A Randomized Controlled Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years inclusive
- ECOG performance status 2 or less
- Histologically confirmed proximal gastric cancer or Siewert type II adenocarcinoma of the esophagogastric junction
- Clinical stage cT1-T3, N0-N+, M0
- Tumor maximum diameter 4 cm or less and esophageal invasion 2 cm or less
- Candidates for radical proximal gastrectomy with feasible R0 resection and functional anastomosis
- Assessed by Multidisciplinary Team as suitable for proximal gastrectomy without neoadjuvant therapy
- Radiographic evidence of localized disease with no distant metastasis
- ASA physical status classification 3 or less
- Adequate bone marrow, liver, kidney, heart, and lung function
- Ability to understand and provide written informed consent
- Willingness and ability to comply with 12-month postoperative follow-up
You will not qualify if you...
- Clinical stage T4 or presence of distant metastasis
- Esophageal invasion exceeding 2 cm
- History of major gastric surgery such as partial or total gastrectomy
- Other malignant tumors within the last 5 years
- Severe organic diseases that prevent safe anesthesia or surgery (e.g., severe heart failure, pulmonary fibrosis)
- Need for emergency surgery due to active gastric bleeding, perforation, or acute obstruction
- Pregnant or breastfeeding women
- Serious psychiatric disorders or cognitive impairment affecting study compliance
- Any condition deemed unsuitable for participation by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China
Actively Recruiting
Research Team
X
Xian Shen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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