Actively Recruiting

Phase Not Applicable
Age: 5Years +
All Genders
NCT04506853

Single-Sided Deafness and Asymmetric Hearing Loss

Led by Med-El Corporation · Updated on 2025-09-24

65

Participants Needed

6

Research Sites

301 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the study is to evaluate the long-term safety and effectiveness of cochlear implantation of the approved population in adults and children with single-sided deafness and asymmetric hearing loss.

CONDITIONS

Official Title

Single-Sided Deafness and Asymmetric Hearing Loss

Who Can Participate

Age: 5Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Five years of age or older at the time of implantation
  • Unilateral profound hearing loss with a pure-tone average of 90 dB or greater in the ear to be implanted
  • Sensorineural hearing loss in the ear to be implanted with an air-bone gap less than or equal to 10 dB at two or more frequencies
  • Normal hearing or mild to moderate hearing loss in the non-implanted ear with a pure-tone average of 55 dB or less
  • Word recognition score of 5% or less on CNC word test in quiet in the ear to be implanted
  • Previous experience with an appropriately-fit CROS hearing aid, BI-CROS hearing aid, bone conduction, or traditional hearing aid
  • Fluent in English
Not Eligible

You will not qualify if you...

  • Duration of profound hearing loss of 10 years or more
  • Absence of cochlear development or non-functionality of cochlear nerve
  • Other retrocochlear hearing loss
  • Evidence of severe cochlear malformation such as common cavity or ossification
  • External or middle ear infection
  • Suspected developmental or cognitive concern
  • Other medical contraindication for surgery or anesthesia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 6 locations

1

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States, 60611

Withdrawn

2

University of Iowa

Iowa City, Iowa, United States, 52242-1078

Actively Recruiting

3

New York Eye and Ear Infirmary

New York, New York, United States, 10003

Actively Recruiting

4

University of North Carolina

Chapel Hill, North Carolina, United States, 27517

Active, Not Recruiting

5

Virginia Mason Medical Center

Seattle, Washington, United States, 98101

Actively Recruiting

6

Sunnybrook Health Sciences Center

Toronto, Ontario, Canada, M4N 3M5

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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