Actively Recruiting
Skeletal Muscle Energetics and Fatiguability in Older Individuals
Led by Johns Hopkins University · Updated on 2026-03-09
200
Participants Needed
1
Research Sites
443 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The investigators are studying whether metabolic abnormalities in calf (leg) muscle in older people with and others without HIV are associated with decreased abilities to exercise.
CONDITIONS
Official Title
Skeletal Muscle Energetics and Fatiguability in Older Individuals
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants who are 60 years of age or older
- HIV positive participants on stable antiretroviral therapy with no regimen change in the last month and undetectable HIV viral load (<100 copies)
- HIV negative participants
You will not qualify if you...
- Unable to understand the risks, benefits, and alternatives of participation and give meaningful consent
- Contraindications to MRI
- Significant cardiovascular, pulmonary, musculoskeletal, or orthopedic disease that significantly limits exercise capacity
- Significant lower extremity peripheral vascular disease
- Weight greater than 350 lbs
- Cognitive or speech impairments that would limit completion of questionnaires or fatigue reporting
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Johns Hopkins Hospital
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
M
Maria Esteban, RN, BSN
CONTACT
T
Tricia Steinberg, RN, MSN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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