Actively Recruiting

Age: 10Years +
All Genders
ID07033169

A Skin Image Reference Tool to Aid Healthcare Providers' Diagnosis of Commonly Encountered Dermatologic Diseases

Led by Wake Forest University Health Sciences · Updated on 2025-10-24

400

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

Sponsors

W

Wake Forest University Health Sciences

Lead Sponsor

B

BelleTorus Corporation

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to evaluate the accuracy of the Belle.ai software in diagnosing common dermatologic diseases across different skin tones. The software uses deep learning technology to analyze clinical images of skin conditions and provides a differential diagnosis from a database of over 2,000 skin conditions based on more than 500,000 images. The study will determine how well the AI-generated diagnoses match those of dermatology experts. Participants who consent will have three images taken of their skin condition using the Belle.ai software. These images will be de-identified and uploaded into the system, where the software will generate a single list of possible diagnoses. Dermatology experts will then review the cases to compare their diagnoses with the AI results. The study will be conducted at dermatology clinics within the Advocate Health system. During the study, images will be captured and uploaded securely without any personal identifiers. The Dermatologic Review Committee will assess the concordance between the AI's primary diagnosis and expert opinions, aiming for greater than 80% agreement. Participants will not need to complete any additional forms, and their involvement primarily involves image capture during their clinic visit. The main outcome measured is the agreement between AI and physician diagnoses on the day of image capture.

CONDITIONS

Brief Title

A Skin Image Reference Tool to Aid Healthcare Providers' Diagnosis

Who Can Participate

Age: 10Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient must present to an Advocate Health dermatology clinic
  • Patient must have the ability and willingness to provide informed consent and comply with study procedures and visits
  • Participant dermatologists must have access to the required technology (e.g., smartphone with internet access) and be capable of using it for the required image capture
  • Participants must be 10 years of age or older
Not Eligible

You will not qualify if you...

  • Patients who are unable to comply with study procedures due to physical or mental health limitations (as assessed by study coordinator)
  • Pediatric, adolescent, and teen patients who present with dermatological conditions on their genitalia will not be included in the study to support patient privacy concerns

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Day 1

Participants have three images taken of their dermatologic disease which are uploaded to the Belle.ai software for AI-generated diagnosis.

1 visit (in-person)

Long-term Monitoring

Duration - Up to study completion in December 2027

Dermatology experts review and adjudicate the AI-generated diagnoses for concordance over time.

Follow-up assessments as needed

Trial Site Locations

Total: 1 location

1

Wake Forest University Health Sciences Department of Dermatology

Winston-Salem, North Carolina, United States, 27157

Actively Recruiting

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Research Team

I

Irma M Richardson, MHA

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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