Actively Recruiting
Skin Involvement in Dupuytren Surgical Treatment Outcome
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2026-03-13
50
Participants Needed
1
Research Sites
107 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Palmar skin is often retracted in Dupuytren disease (DD), making surgical management challenging and skin-preserving surgery difficult. Based on clinical experience in DD surgery and outcome, it is suspected that recurrence may be associated with such retracted skin. Possibly, this is due to presence and persistence of aligned myofibroblasts (MF), fixed to the deepest dermal layers. This interventional study aims to investigate the pathophysiological involvement of palmar skin in Dupuytren disease, and its implications for prognostics and treatment.
CONDITIONS
Official Title
Skin Involvement in Dupuytren Surgical Treatment Outcome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntary written informed consent obtained before screening
- Patients aged 18 years or older diagnosed with primary Dupuytren disease
- Patients scheduled for microfasciectomy surgery
You will not qualify if you...
- Previous Dupuytren surgery on the hand scheduled for microfasciectomy
- Unable to provide written consent
- Younger than 18 years old
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Universitaire Ziekenhuizen KU Leuven
Leuven, Vlaams-Brabant, Belgium, 3000
Actively Recruiting
Research Team
I
Ilse Degreef, Prof. Dr.
CONTACT
A
Anna Tarasiuk
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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