Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT05401292

Skin Preparation for Elective Foot and Ankle Surgery

Led by University of Missouri-Columbia · Updated on 2026-04-27

100

Participants Needed

1

Research Sites

250 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Surgical site infections (SSIs) make about 31% of all nosocomial infections and they are the most common hospital-acquired infection. For foot and ankle elective interventions, SSI rate is reported between 0.4% and 3.6%. This study will investigate the effectiveness of skin cleaning with isopropyl alcohol and scrubbing with chlorhexidine soap before standard skin preparation in reducing microbial load and surgical site infections for elective foot and ankle surgeries. Current standard of care includes skin preparation with iodine or chlorhexidine solution prior to sterile draping and the start of surgery. Standard of care will be applied to all patients. The use of an additional "pre-scrub" with isopropyl alcohol and scrubbing with chlorhexidine soap will be applied to the experimental group. The control group will receive only the standard of care skin preparation with iodine or chlorhexidine solution prior to draping.

CONDITIONS

Official Title

Skin Preparation for Elective Foot and Ankle Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing elective foot and ankle surgeries
  • Age over 18
Not Eligible

You will not qualify if you...

  • Trauma as the indication for surgery
  • Open injuries
  • Non-elective procedures
  • Amputations
  • Prior surgical site infection through the planned incision
  • Pregnancy. All potential participants of child-bearing potential follow the standard pre-operative protocol to ensure they are not in pregnant status prior to SOC surgical procedure.

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Missouri

Columbia, Missouri, United States, 65211

Actively Recruiting

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Research Team

V

Vicki L Jones, MEd, CCRP

CONTACT

K

Kyle Schweser, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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