Actively Recruiting
Skin Wetting in Burn Survivors
Led by University of Texas Southwestern Medical Center · Updated on 2025-10-21
40
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This project will identify the efficacy of whole body skin wetting aimed to attenuate excessive elevations in internal body temperatures during physical activity in well-healed burn survivors. The investigators will conduct a randomized crossover design study. Non-burned control subjects, subjects who experienced burns covering \~20% to 40% of their body surface area, and subject having burns \>40% of their body surface area will be investigated. Subjects will exercise in heated environmental conditions while receiving no cooling or whole body skin wetting.
CONDITIONS
Official Title
Skin Wetting in Burn Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy males and females aged 18 to 65 years
- Free of any underlying medical conditions
- For burn survivors: burn injury covering 20-40% or more than 40% of body surface area, with at least 50% full thickness burns requiring skin grafting
- For burn survivors: hospitalization for burn injury of at least 15 days
- Non-burned healthy males and females aged 18 to 65 years
You will not qualify if you...
- Any burn injury resulting in at least one night of hospitalization (for non-burn survivors)
- Heart disease or any chronic medical condition requiring regular medical treatment including cancer, diabetes, or hypertension
- Abnormalities detected on routine screening
- Participation in structured aerobic exercise training at moderate to high intensities
- Current smokers or those who smoked regularly within the past 3 years
- Body mass index greater than 30 kg/m^2
- Pregnancy
- Extensive unhealed injured skin (for burn survivors)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Institute for Exercise and Environmental Medicine
Dallas, Texas, United States, 75231
Actively Recruiting
Research Team
C
Craig Crandall, PhD
CONTACT
E
Erin Harper, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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