Actively Recruiting

Phase Not Applicable
Age: 25Years - 64Years
All Genders
NCT05184933

Sleep and Circadian Mechanisms in Hypertension

Led by Oregon Health and Science University · Updated on 2026-02-11

32

Participants Needed

1

Research Sites

347 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).

CONDITIONS

Official Title

Sleep and Circadian Mechanisms in Hypertension

Who Can Participate

Age: 25Years - 64Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 25-64
  • Body mass index (BMI) between 18.5 and 42 kg/m2
  • Hypertension with average resting blood pressure between 130/80 mmHg and 160/100 mmHg
Not Eligible

You will not qualify if you...

  • More than 5 pack-years of smoking
  • Shift work within 12 months prior to the study
  • Travel across more than three time zones within the last 3 months
  • History of heart failure, cardiomyopathy, bypass surgery, angioplasty, or previous myocardial infarction
  • Acute or chronic diseases other than hypertension that may affect study results
  • History of psychological conditions
  • Sleep disorders such as severe sleep apnea or insomnia
  • Use of prescription medications except contraceptives and anti-hypertensive drugs
  • History of illicit drug use or alcohol dependency
  • Cannabis use within 30 days prior to the study
  • Pregnancy
  • Blood pressure exceeding 160/100 mmHg

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Oregon Health and Science University

Portland, Oregon, United States, 97239

Actively Recruiting

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Research Team

N

Nicole Chaudhary, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Sleep and Circadian Mechanisms in Hypertension | DecenTrialz